Intersphincteric Resection for Low Rectal Cancer: Parameters Affecting Functional Outcomes and Survival Rates

医学 结肠造口术 结直肠癌 远处转移 放化疗 外科 总体生存率 放射治疗 癌症 转移 内科学
作者
Vusal Aliyev,Beslen Göksoy,Süha Göksel,Koray Güven,Barış Bakır,Sezer Sağlam,Oktar Asoğlu
出处
期刊:Surgical technology international [Universal Medical Press]
卷期号:39 被引量:10
标识
DOI:10.52198/21.sti.39.cr1460
摘要

Introduction: The development of new surgical techniques and devices, as well as the improvements in neoadjuvant chemoradiotherapy enabled intersphincteric resection (ISR), has reduced permanent colostomy usage. The aim of this study was to assess the long-term oncological and functional outcomes of patients who underwent partial ISR for rectal cancer located less than 5cm from the anal verge. Materials and Methods: A series of 106 consecutive patients with very low rectal cancer underwent curative partial ISR from January 2006 to September 2019 were retrospectively evaluated. One-hundred-three (97%) of 106 patients received neoadjuvant chemo-radiotherapy. Overall survival (OS), disease-free survival (DFS), and local recurrence (LR) rates were calculated using Kaplan–Meier methods. The Wexner incontinence score and Kirwan classification were used to evaluate patients’ functional results. Results: The median follow up was 60 months (range, 18–174). The estimated five-year overall and disease-free survival rates were 89% and 81.6%, respectively. Five-year local recurrence and distant metastasis rates were 6.6% and 10.4%, respectively. There was no in-hospital and 30-day mortality. The median Wexner score was 9 (range, 0–20) for 72 patients. Age (<65 years, p=0.027) and gender (male, p=0.019) had a positive effect on functional outcomes after surgery. One and five years colostomy-free survival rates were 96% and 89%, respectively. Conclusion: Intersphincteric resection techniques are feasible for patients with very low rectal cancer, providing good oncological and functional outcomes.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
傲娇颖完成签到,获得积分10
1秒前
ShellyMaya完成签到 ,获得积分10
2秒前
3秒前
一只大憨憨猫完成签到,获得积分10
3秒前
JJ完成签到,获得积分10
3秒前
DrW完成签到,获得积分10
3秒前
隐形曼青应助yue采纳,获得10
4秒前
ccyy完成签到 ,获得积分10
4秒前
NexusExplorer应助腾腾腾采纳,获得10
5秒前
宿帅帅完成签到,获得积分10
6秒前
6秒前
Ningxin完成签到,获得积分10
6秒前
HHEHK发布了新的文献求助10
6秒前
柚子完成签到 ,获得积分10
6秒前
雨辰完成签到,获得积分10
8秒前
宿帅帅发布了新的文献求助10
8秒前
量子星尘发布了新的文献求助10
11秒前
11秒前
熠熠完成签到,获得积分10
11秒前
12秒前
zxzb完成签到,获得积分10
14秒前
苹果萧完成签到 ,获得积分10
17秒前
宋江他大表哥完成签到,获得积分10
17秒前
able发布了新的文献求助10
17秒前
王先生完成签到 ,获得积分10
18秒前
H.发布了新的文献求助10
18秒前
luoluo完成签到,获得积分10
19秒前
19秒前
高分子完成签到,获得积分10
19秒前
yian发布了新的文献求助10
20秒前
yar应助体贴凌柏采纳,获得10
21秒前
自由的雪一完成签到,获得积分10
21秒前
Ava应助李振博采纳,获得200
21秒前
JW发布了新的文献求助10
22秒前
无限的千凝完成签到 ,获得积分10
23秒前
CipherSage应助YeeYee采纳,获得10
23秒前
23秒前
Ander完成签到 ,获得积分10
24秒前
化白完成签到,获得积分10
25秒前
H.完成签到,获得积分10
25秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038303
求助须知:如何正确求助?哪些是违规求助? 3576013
关于积分的说明 11374210
捐赠科研通 3305780
什么是DOI,文献DOI怎么找? 1819322
邀请新用户注册赠送积分活动 892672
科研通“疑难数据库(出版商)”最低求助积分说明 815029