Intersphincteric Resection for Low Rectal Cancer: Parameters Affecting Functional Outcomes and Survival Rates

医学 结肠造口术 结直肠癌 远处转移 放化疗 外科 总体生存率 放射治疗 癌症 转移 内科学
作者
Vusal Aliyev,Beslen Göksoy,Süha Göksel,Koray Güven,Barış Bakır,Sezer Sağlam,Oktar Asoğlu
出处
期刊:Surgical technology international [Universal Medical Press]
卷期号:39 被引量:10
标识
DOI:10.52198/21.sti.39.cr1460
摘要

Introduction: The development of new surgical techniques and devices, as well as the improvements in neoadjuvant chemoradiotherapy enabled intersphincteric resection (ISR), has reduced permanent colostomy usage. The aim of this study was to assess the long-term oncological and functional outcomes of patients who underwent partial ISR for rectal cancer located less than 5cm from the anal verge. Materials and Methods: A series of 106 consecutive patients with very low rectal cancer underwent curative partial ISR from January 2006 to September 2019 were retrospectively evaluated. One-hundred-three (97%) of 106 patients received neoadjuvant chemo-radiotherapy. Overall survival (OS), disease-free survival (DFS), and local recurrence (LR) rates were calculated using Kaplan–Meier methods. The Wexner incontinence score and Kirwan classification were used to evaluate patients’ functional results. Results: The median follow up was 60 months (range, 18–174). The estimated five-year overall and disease-free survival rates were 89% and 81.6%, respectively. Five-year local recurrence and distant metastasis rates were 6.6% and 10.4%, respectively. There was no in-hospital and 30-day mortality. The median Wexner score was 9 (range, 0–20) for 72 patients. Age (<65 years, p=0.027) and gender (male, p=0.019) had a positive effect on functional outcomes after surgery. One and five years colostomy-free survival rates were 96% and 89%, respectively. Conclusion: Intersphincteric resection techniques are feasible for patients with very low rectal cancer, providing good oncological and functional outcomes.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
li发布了新的文献求助30
1秒前
3秒前
日辰彗心发布了新的文献求助10
4秒前
无花果应助冷傲小猫咪采纳,获得10
4秒前
8湖公园发布了新的文献求助10
5秒前
6秒前
Leoling完成签到,获得积分10
6秒前
打打应助xrc采纳,获得10
6秒前
烛光发布了新的文献求助10
6秒前
大个应助勤恳的夏之采纳,获得10
7秒前
欣慰薯片完成签到,获得积分10
7秒前
一如果一完成签到,获得积分10
8秒前
8秒前
北城发布了新的文献求助10
9秒前
练习时长两年半应助全齐采纳,获得10
9秒前
爱宝乐宝福宝应助高梦雪采纳,获得20
9秒前
9秒前
11秒前
11秒前
11秒前
plasma发布了新的文献求助10
12秒前
领导范儿应助澡雪采纳,获得10
12秒前
NexusExplorer应助万晓博采纳,获得10
12秒前
13秒前
归尘发布了新的文献求助30
13秒前
13秒前
干冷安发布了新的文献求助10
14秒前
15秒前
16秒前
16秒前
Barney发布了新的文献求助10
16秒前
17秒前
17秒前
mx发布了新的文献求助10
17秒前
123发布了新的文献求助10
19秒前
lyc45491314发布了新的文献求助20
19秒前
700w完成签到 ,获得积分0
19秒前
量子星尘发布了新的文献求助10
19秒前
20秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Effective Learning and Mental Wellbeing 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3975836
求助须知:如何正确求助?哪些是违规求助? 3520174
关于积分的说明 11201364
捐赠科研通 3256576
什么是DOI,文献DOI怎么找? 1798362
邀请新用户注册赠送积分活动 877539
科研通“疑难数据库(出版商)”最低求助积分说明 806426