催化作用
芳基
化学
铑
化学计量学
还原消去
组合化学
金属
过渡金属
氧化还原
偶联反应
无机化学
氧化加成
有机化学
烷基
作者
Zheng‐Jian Wu,Feng Su,Weidong Lin,Jinshuai Song,Ting‐Bin Wen,Hui‐Jun Zhang,Hai‐Chao Xu
标识
DOI:10.1002/anie.201909951
摘要
Abstract Transition metal catalyzed C−H phosphorylation remains an unsolved challenge. Reported methods are generally limited in scope and require stoichiometric silver salts as oxidants. Reported here is an electrochemically driven Rh III ‐catalyzed aryl C−H phosphorylation reaction that proceeds through H 2 evolution, obviating the need for stoichiometric metal oxidants. The method is compatible with a variety of aryl C−H and P−H coupling partners and particularly useful for synthesizing triarylphosphine oxides from diarylphosphine oxides, which are often difficult coupling partners for transition metal catalyzed C−H phosphorylation reactions. Experimental results suggest that the mechanism responsible for the C−P bond formation involves an oxidation‐induced reductive elimination process.
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