Preterm Delivery and Future Risk of Maternal Cardiovascular Disease: A Systematic Review and Meta‐Analysis

医学 荟萃分析 相对风险 冲程(发动机) 混淆 胎龄 早产 疾病 怀孕 内科学 置信区间 产科 机械工程 生物 工程类 遗传学
作者
Pensée Wu,Martha Gulati,Chun Shing Kwok,Chun Wai Wong,Aditya Narain,Shaughn O’Brien,Carolyn Chew‐Graham,Ganga Ram Verma,Umesh Kadam,Mamas A. Mamas
出处
期刊:Journal of the American Heart Association [Ovid Technologies (Wolters Kluwer)]
卷期号:7 (2) 被引量:104
标识
DOI:10.1161/jaha.117.007809
摘要

Background Preterm delivery (<37 weeks gestational age) affects 11% of all pregnancies, but data are conflicting whether preterm birth is associated with long‐term adverse maternal cardiovascular outcomes. We aimed to systematically evaluate and summarize the evidence on the relationship between preterm birth and future maternal risk of cardiovascular diseases. Methods and Results A systematic search of MEDLINE and EMBASE was performed to identify relevant studies that evaluated the association between preterm birth and future maternal risk of composite cardiovascular disease, coronary heart disease, stroke, and death caused by cardiovascular or coronary heart disease and stroke. We quantified the associations using random effects meta‐analysis. Twenty‐one studies with over 5.8 million women, including over 338 000 women with previous preterm deliveries, were identified. Meta‐analysis of studies that adjusted for potential confounders showed that preterm birth was associated with an increased risk of maternal future cardiovascular disease (risk ratio [ RR ] 1.43, 95% confidence interval [CI], 1.18, 1.72), cardiovascular disease death ( RR 1.78, 95% CI , 1.42, 2.21), coronary heart disease ( RR 1.49, 95% CI , 1.38, 1.60), coronary heart disease death ( RR 2.10, 95% CI , 1.87, 2.36), and stroke ( RR 1.65, 95% CI , 1.51, 1.79). Sensitivity analysis showed that the highest risks occurred when the preterm deliveries occurred before 32 weeks gestation or were medically indicated. Conclusions Preterm delivery is associated with an increase in future maternal adverse cardiovascular outcomes, including a 2‐fold increase in deaths caused by coronary heart disease. These findings support the assessment of preterm delivery in cardiovascular risk assessment in women.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
C2H5MgBr完成签到,获得积分10
刚刚
刚刚
TT发布了新的文献求助10
刚刚
ss13l完成签到,获得积分10
刚刚
润润轩轩发布了新的文献求助10
刚刚
大个应助学术卷心菜采纳,获得10
刚刚
夏沫完成签到,获得积分10
1秒前
muek发布了新的文献求助10
1秒前
王振军完成签到,获得积分10
2秒前
3秒前
3秒前
科研通AI2S应助研友_8op5gL采纳,获得10
3秒前
afterall完成签到 ,获得积分10
4秒前
北林完成签到,获得积分10
4秒前
元谷雪完成签到,获得积分10
5秒前
壮壮女士完成签到,获得积分10
5秒前
龙卷风发布了新的文献求助10
5秒前
mingruiqi完成签到,获得积分10
5秒前
火星上的冬云完成签到,获得积分20
5秒前
撒啊完成签到,获得积分10
5秒前
高高发布了新的文献求助20
6秒前
风吹草动玉米粒完成签到,获得积分10
6秒前
炼金术士完成签到,获得积分10
7秒前
8秒前
称心小兔子完成签到,获得积分10
8秒前
8秒前
眼睛大又蓝完成签到,获得积分20
9秒前
9秒前
皓月孤烟发布了新的文献求助10
10秒前
万能图书馆应助晓舟采纳,获得10
10秒前
Joyj99完成签到,获得积分10
10秒前
太师完成签到,获得积分10
11秒前
协和小飞龙完成签到,获得积分10
11秒前
12秒前
12秒前
李清湛完成签到,获得积分10
12秒前
13秒前
anyang完成签到,获得积分10
13秒前
14秒前
14秒前
高分求助中
The late Devonian Standard Conodont Zonation 2000
The Lali Section: An Excellent Reference Section for Upper - Devonian in South China 1500
Nickel superalloy market size, share, growth, trends, and forecast 2023-2030 1000
Smart but Scattered: The Revolutionary Executive Skills Approach to Helping Kids Reach Their Potential (第二版) 1000
Mantiden: Faszinierende Lauerjäger Faszinierende Lauerjäger 800
PraxisRatgeber: Mantiden: Faszinierende Lauerjäger 800
A new species of Coccus (Homoptera: Coccoidea) from Malawi 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3244993
求助须知:如何正确求助?哪些是违规求助? 2888606
关于积分的说明 8254294
捐赠科研通 2557053
什么是DOI,文献DOI怎么找? 1385683
科研通“疑难数据库(出版商)”最低求助积分说明 650212
邀请新用户注册赠送积分活动 626403