医学
体外膜肺氧合
四分位间距
急性呼吸窘迫综合征
恶性肿瘤
呼吸衰竭
人口统计学的
外科
肺移植
麻醉
充氧
移植
回顾性队列研究
肺
内科学
人口学
社会学
作者
Andja Bojic,Peter Schellongowski,Oliver Robak,Alexander Hermann,Nina Buchtele,Bernhard Nagler,Wolfgang Lamm,Thomas Staudinger
出处
期刊:Asaio Journal
[Ovid Technologies (Wolters Kluwer)]
日期:2020-07-27
卷期号:67 (3): 345-352
被引量:5
标识
DOI:10.1097/mat.0000000000001225
摘要
The duration of extracorporeal membrane oxygenation (ECMO) treatments increases, however, data presented from prolonged support is limited. We retrospectively analyzed all patients during a 4-year period undergoing respiratory ECMO for duration of therapy, demographics, therapy-associated parameters, and outcome according to ECMO duration (<28 days and ≥28 days = long-term ECMO). Out of 55 patients undergoing ECMO for ARDS or during bridging to lung transplantation, 18 were on ECMO for ≥28 days (33%). In the long-term group, median ECMO run time was 40 days (interquartile range 34-54 days). Hospital survival was not significantly different between the groups (54% in short-term and 50% in long-term ECMO patients). There was a significantly higher proportion of patients suffering from malignancy in the group of long-term nonsurvivors. Recovery occurred after more than 40 days on ECMO in 3 patients. The longest ECMO run time in a hospital survivor was 65 days. Duration of ECMO support alone was no prognostic factor and should not represent a basis for decision-making. In patients suffering from malignancy, long-term ECMO support seems to be a factor of adverse prognosis, if not futile.
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