生物
鸟嘌呤核苷酸交换因子
生物发生
拉布
细胞器生物发生
细胞器
GTP酶
细胞生物学
遗传学
基因
出处
期刊:Current Biology
[Elsevier BV]
日期:2012-11-01
卷期号:22 (22): R963-R965
被引量:10
标识
DOI:10.1016/j.cub.2012.10.005
摘要
Prominent subtypes of the genetic disorder Hermansky-Pudlak syndrome result from defects in a mysterious protein complex, BLOC-3. New work identifies BLOC-3 as a guanine nucleotide exchange factor for two RAB GTPases previously implicated in lysosome-related organelle biogenesis.
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