作者
Elizabeth Asbury,Nasim Kanji,Edzard Ernst,Mahmoud Barbir,Peter Collins
摘要
In Brief Objectives: To explore autogenic training (AT) as a treatment for psychological morbidity, symptomology, and physiological markers of stress among women with chest pain, a positive exercise test for myocardial ischemia, and normal coronary arteries (cardiac syndrome X). Design: Fifty-three women with cardiac syndrome X (mean ± SD age, 57.1 ± 8 years) were randomized to an 8-week AT program or symptom diary control. Symptom severity and frequency, Hospital Anxiety and Depression Scale, Spielberger State-Trait Anxiety Inventory, Cardiac Anxiety Questionnaire (CAQ), and Ferrans and Powers Quality of Life Index (QLI), blood pressure, heart rate, electrocardiogram, and plasma catecholamines were measured before and after intervention and at the 8-week follow-up. Results: Women who underwent AT had improved symptom frequency (8.04 ± 10.08 vs 1.66 ± 2.19, P < 0.001) compared with control women and reduced symtom severity (2.08 ± 1.03 vs 1.23 ± 1.36, P = 0.02) and frequency (6.11 ± 3.17 vs 1.66 ± 2.19, P < 0.001) post-AT compared with baseline within group. Within-group improvements among women who underwent AT include QLI health functioning (17.80 ± 5.74 vs 19.41 ± 5.19, P = 0.04) and CAQ fear (1.53 ± 0.61 vs 1.35 ± 0.56, P = 0.02) post-AT and QLI health functioning (17.80 ± 5.74 vs 20.09 ± 5.47, P = 0.01), CAQ fear (1.53 ± 0.61 vs 1.30 ± 0.67, P = 0.002), CAQ total (1.42 ± 0.54 vs 1.29 ± 0.475, P = 0.04), Spielberger State-Trait Anxiety Inventory trait anxiety (42.95 ± 11.19 vs 38.68 ± 11.47, P = 0.01), and QLI quality of life (20.67 ± 5.37 vs 21.9 ± 4.89, P = 0.02) at follow-up. Conclusion: An 8-week AT program improves symptom frequency, with near-significant improvements in symptom severity in women with cardiac syndrome X. Chest pain in the presence of angiographically normal coronary arteries and a positive stress test for myocardial ischaemia, Cardiac Syndrome X, is a debilitating condition with few treatment options. Autogenic Training, a relaxation therapy, has been shown to improve symptomology among a female patient population.