医学
麻醉
通风(建筑)
高频通风
低氧血症
机械通风
肺
通气灌注不匹配
重症监护
功能剩余容量
充氧
内科学
肺容积
重症监护医学
机械工程
工程类
作者
Kendra M. Smith,Jeanne D. Mrozek,Susan C. Simonton,Dennis R. Bing,Pat A. Meyers,John E. Connett,Mark C. Mammel
出处
期刊:Critical Care Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:1997-11-01
卷期号:25 (11): 1888-1897
被引量:231
标识
DOI:10.1097/00003246-199711000-00030
摘要
In this animal model, partial liquid ventilation using conventional or high-frequency ventilation provided rapid and sustained improvements in oxygenation without adverse hemodynamic consequences. Animals treated with partial liquid ventilation-flow interruption had a significantly decreased survival rate vs. animals treated with the other studied techniques. Histopathologic and morphometric analysis showed significantly less injury in the lower lobes of lungs from animals treated with partial liquid ventilation. High-frequency ventilation techniques did not further improve pathologic outcome.
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