特应性皮炎
殖民地化
极性(国际关系)
医学
皮肤病科
金黄色葡萄球菌
免疫学
微生物学
生物
细菌
遗传学
细胞
作者
Jill A. Warner,Laura Y. McGirt,Lisa A. Beck
标识
DOI:10.1111/j.1365-2133.2008.08905.x
摘要
Background Staphylococcal colonization of the skin is commonly observed in subjects with atopic dermatitis (AD) and correlates with disease severity. Little is known about whether the degree of T-helper 2 (Th2) polarity in these subjects can also affect the frequency of bacterial colonization in this disease. Objectives To determine if there is a correlation between markers of Th2 polarity [serum total IgE, eosinophilia and presence of another atopic disease (allergic rhinitis)] and skin colonization with Staphylococcus aureus in subjects with AD. Methods A retrospective chart review was performed of an academic dermatology clinic focused on the treatment of AD with a single provider. Results Staphylococcus aureus colonization was more commonly observed in subjects with AD who had peripheral eosinophilia, elevated serum IgE levels, and/or a history of or active allergic rhinitis. Conclusions Results suggest that Th2 polarity may enhance subjects' risk for bacterial colonization.
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