Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer

医学肿瘤浸润淋巴细胞肿瘤科内科学浆液性液体卵巢癌生存分析 CD8型免疫疗法癌症免疫系统免疫学

作者

Ellen L. Goode,Matthew S. Block,Kimberly R. Kalli,Robert A. Vierkant,Wenqian Chen,Zachary C. Fogarty,Aleksandra Gentry‐Maharaj,Aleksandra Tołoczko,Alexander Hein,Aliecia L. Bouligny,Allan Jensen,Ana Osório,Andreas D. Hartkopf,Andy Ryan,Anita Chudecka-Głaz,Anthony M. Magliocco,Arndt Hartmann,Audrey Jung,Bo Gao,Brenda Y. Hernandez,Brooke L. Fridley,Bryan M. McCauley,Catherine J. Kennedy,Chen Wang,Chloe Karpinskyj,Christiani Bisinoto de Sousa,Daniel Guimarães Tiezzi,David L. Wachter,Esther Herpel,Florin‐Andrei Taran,Francesmary Modugno,Gregg Nelson,Jan Lubiński,Janusz Menkiszak,Jennifer Alsop,Jenny Lester,Jesús García-Donás,Jill Nation,Jillian A. Hung,José Palacios,Joseph H. Rothstein,Joseph L. Kelley,Jurandyr Moreira de Andrade,Luis A. Díaz‐Robles,Maria P. Intermaggio,Martin Widschwendter,Matthias W. Beckmann,Matthias Ruebner,Mercedes Jimenez‐Liñan,Naveena Singh,Oleg Oszurek,Paul R. Harnett,Peter Rambau,Hans‐Peter Sinn,Philipp Wagner,Prafull Ghatage,Raghwa Sharma,Robert P. Edwards,Roberta B. Ness,Sandra Oršulić,Sara Y. Brucker,Sharon E. Johnatty,Teri A. Longacre,Ursula Eilber,Valerie McGuire,Weiva Sieh,Yanina Natanzon,Zheng Li,Alice S. Whittemore,Anna deFazio,Annette Staebler,Beth Y. Karlan,C. Blake Gilks,David D.L. Bowtell,Estrid Høgdall,Francisco José Cândido dos Reis,Helen Steed,Ian Campbell,Jacek Gronwald,Javier Benı́tez,Jennifer M. Koziak,Jenny Chang‐Claude,Kirsten B. Moysich,Linda E. Kelemen,Linda S. Cook,Marc T. Goodman,María J. García,Peter A. Fasching,Stefan Kommoss,Suha Deen,Susanne K. Kjær,Usha Menon,James D. Brenton,Paul D.P. Pharoah,Georgia Chenevix‐Trench,David G. Huntsman,Stacey J. Winham,Martin Köbel,Susan J. Ramus

出处

期刊：JAMA Oncology [American Medical Association]
日期：2017-10-19 卷期号：3 (12): e173290-e173290 被引量：302

链接

jamanetwork.com europepmc.org europepmc.org nih.gov nih.govdoi.org

标识

DOI：10.1001/jamaoncol.2017.3290

摘要

Cytotoxic CD8+ tumor-infiltrating lymphocytes (TILs) participate in immune control of epithelial ovarian cancer; however, little is known about prognostic patterns of CD8+ TILs by histotype and in relation to other clinical factors.

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Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer

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