Patterns of Relapse after Definitive Chemoradiotherapy in Stage II/III (Non-T4) Esophageal Squamous Cell Carcinoma

医学 食管胃十二指肠镜检查 胃肠病学 放化疗 食管癌 内科学 阶段(地层学) 食管鳞状细胞癌 癌症 内窥镜检查 生物 古生物学
作者
Kazuki Sudo,Ken Kato,Hiroki Kuwabara,Yusuke Sasaki,Naoki Takahashi,Hirokazu Shoji,Satoru Iwasa,Yoshitaka Honma,Natsuko Okita,Atsuo Takashima,Tetsuya Hamaguchi,Yasuhide Yamada,Yoshinori Ito,Jun Itami,Takahiro Fukuda,Kensei Tobinai,Narikazu Boku
出处
期刊:Oncology [Karger Publishers]
卷期号:94 (1): 47-54 被引量:14
标识
DOI:10.1159/000480515
摘要

The purpose of this study was to investigate the utility of surveillance after definitive chemoradiotherapy (dCRT) in patients with squamous cell carcinoma.Patients who underwent dCRT for stage II/III (excluding T4) esophageal squamous cell carcinoma were analyzed. First failures following complete response were classified into luminal relapse (LR), regional relapse (RR), distant metastasis (DM), new cancer diagnosed by esophagogastroduodenoscopy (NC-E), and new cancer other than NC-E (NC-O). We focused on LR, RR, and NC-E, and analyzed their frequency, timings and survival outcomes after local treatments.Among 302 patients treated with dCRT, 204 achieved complete response. The number of patients who recurred with LR, RR, DM, NC-E, and NC-O were 28 (14% of 204), 13 (6%), 39 (19%), 34 (17%), and 16 (8%). Ninety-three percent of LRs were diagnosed within 3 years after dCRT, and all RRs were diagnosed within 2 years. Annual odds of NC-E did not decrease over time. Twenty-three patients with LR, 6 with RR, and 32 with NC-E underwent local treatment, and their median overall survivals were 49.2, 19.5, and 108.9 months.Surveillance with esophagogastroduodenoscopy may be important in the first 3 years after dCRT to detect LR and to detect NC-E beyond 3 years.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
swapping完成签到 ,获得积分10
刚刚
彭栋发布了新的文献求助10
2秒前
所所应助萨日呼采纳,获得10
3秒前
5秒前
隐形曼青应助hh采纳,获得50
7秒前
义气如萱发布了新的文献求助10
8秒前
小俊完成签到,获得积分10
10秒前
Nana发布了新的文献求助20
11秒前
小二郎应助修管子采纳,获得10
12秒前
mie完成签到,获得积分10
15秒前
15秒前
16秒前
寄语明月发布了新的文献求助10
18秒前
hh发布了新的文献求助50
20秒前
mie发布了新的文献求助10
20秒前
CipherSage应助wu基督教采纳,获得10
21秒前
lalala完成签到,获得积分10
22秒前
科研通AI5应助Bressanone采纳,获得10
23秒前
23秒前
25秒前
FashionBoy应助anna采纳,获得10
30秒前
30秒前
32秒前
大智若愚骨头完成签到,获得积分10
33秒前
33秒前
36秒前
量子星尘发布了新的文献求助10
36秒前
9℃发布了新的文献求助10
36秒前
科研通AI2S应助lm采纳,获得10
37秒前
山谷发布了新的文献求助10
38秒前
感动黄豆发布了新的文献求助10
40秒前
42秒前
43秒前
43秒前
43秒前
45秒前
Owen应助晒太阳的加菲猫采纳,获得10
46秒前
anna发布了新的文献求助10
48秒前
48秒前
wu基督教发布了新的文献求助10
49秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989115
求助须知:如何正确求助?哪些是违规求助? 3531367
关于积分的说明 11253688
捐赠科研通 3269986
什么是DOI,文献DOI怎么找? 1804868
邀请新用户注册赠送积分活动 882078
科研通“疑难数据库(出版商)”最低求助积分说明 809105