镁
催化作用
化学
组合化学
生化工程
有机化学
纳米技术
材料科学
工程类
作者
Dongxu Yang,Linqing Wang,Dan Li,Rui Wang
出处
期刊:Chem
[Elsevier]
日期:2019-05-01
卷期号:5 (5): 1108-1166
被引量:45
标识
DOI:10.1016/j.chempr.2019.02.002
摘要
Magnesium (Mg) is an alkaline earth metal that is quite abundant on our planet. Considering the resource constraints on earth, developing synthetic methods by using catalysts derived from abundant resources is key to sustainable chemistry. However, the application of magnesium-catalyzed reactions remains very limited, and such methods have attracted relatively little attention. The emerging novel catalytic strategies with magnesium can be applied in a wide range of basic chemical transformations by taking advantage of the unique characteristics of different types of magnesium salts. Efficient reactions with Mg(II) catalysts could serve as practical and low-cost synthetic methods for assembling valuable molecular skeletons in a sustainable way. In reviewing magnesium-catalyzed asymmetric reactions, we discuss the two general strategies for generating chiral organometallic Mg(II) complexes. Magnesium is one of the most abundant metals on earth and can be applied in a wide range of fundamental asymmetric reactions. However, compared with those of many other metals, the design and application of magnesium catalysts in asymmetric reactions are relatively limited. In this review, we provide insightful discussions of the catalytic strategies associated with Mg(II) catalysts, related mechanism considerations, and current limitations, as well as the opportunities associated with greater focus on magnesium catalysts in chemical synthesis. In reviewing magnesium-catalyzed asymmetric reactions, we discuss the two general strategies for generating chiral organometallic Mg(II) complexes. Magnesium is one of the most abundant metals on earth and can be applied in a wide range of fundamental asymmetric reactions. However, compared with those of many other metals, the design and application of magnesium catalysts in asymmetric reactions are relatively limited. In this review, we provide insightful discussions of the catalytic strategies associated with Mg(II) catalysts, related mechanism considerations, and current limitations, as well as the opportunities associated with greater focus on magnesium catalysts in chemical synthesis.
科研通智能强力驱动
Strongly Powered by AbleSci AI