Three-dimensional fluorinated covalent organic frameworks coated capillary for the separation of fluoroquinolones by capillary electrochromatography

毛细管电色谱 化学 毛细管作用 色谱法 共价键 毛细管电泳 离子液体 电色谱法 分辨率(逻辑) 分析化学(期刊) 有机化学 材料科学 复合材料 人工智能 计算机科学 催化作用
作者
Han Yin,Ziyi Zhen,Weijie Ning,Lu Zhang,Yuhong Xiang,Nengsheng Ye
出处
期刊:Journal of Chromatography A [Elsevier BV]
卷期号:1706: 464234-464234 被引量:10
标识
DOI:10.1016/j.chroma.2023.464234
摘要

In this work, a three-dimensional fluorinated covalent organic frameworks (3D FCOFs) JUC-515 was synthesized from tetra(4-aminophenyl)methane (TAM) and 2,3,5,6-tetrafluoroterephthalol (TFA) by an ionic liquid method. JUC-515 was introduced into the capillary column and bonded to the inner wall of the capillary column by chemical bonding. Through a variety of characterization results, JUC-515 was successfully synthesized and introduced into the capillary column. The effects of buffer solution concentration, organic additive content and pH of the buffer solution on the separation of fluoroquinolones (FQs) were investigated in detail. The JUC-515-coated capillary column showed good resolution (>1.5) and reproducibility. The relative standard deviations (RSDs) of the retention time for intraday, interday, column-to-column and interbatch precision were less than 0.88%, 2.45%, 2.74% and 3.32%, respectively. The RSDs of the peak area for intraday, interday, column-to-column and interbatch precision were less than 3.79%, 4.31%, 3.33% and 5.62%, respectively. The JUC-515-coated capillary column could be used no less than 150 times. The results showed that the JUC-515-coated capillary column had good separation performance. In addition, by separating fluorinated β-phenylalanine analogs, β-phenylalanine and trifluoromethyl β-phenylalanine analogs, the separation mechanism based on fluorine interactions was discussed. In conclusion, JUC-515 had good potential as a stationary phase for capillary electrochromatography.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
刚刚
1秒前
完美的友蕊应助LJQ采纳,获得10
1秒前
1秒前
yiyi完成签到 ,获得积分10
1秒前
wufeng发布了新的文献求助10
2秒前
科目三应助maomao采纳,获得10
2秒前
2秒前
FashionBoy应助发C刊的人采纳,获得10
2秒前
乐乐应助zhangfan采纳,获得10
3秒前
4秒前
wang发布了新的文献求助10
4秒前
NiNi发布了新的文献求助10
4秒前
SciGPT应助小敏哼采纳,获得10
5秒前
Cici发布了新的文献求助10
5秒前
梁上小偷发布了新的文献求助10
5秒前
ZYH完成签到 ,获得积分10
5秒前
HANK2024发布了新的文献求助10
6秒前
6秒前
Lucas应助小白采纳,获得10
7秒前
糖糖发布了新的文献求助30
8秒前
9秒前
小祺完成签到,获得积分10
9秒前
9秒前
9秒前
10秒前
南冥完成签到 ,获得积分10
10秒前
MYC007完成签到 ,获得积分10
11秒前
11秒前
柚子完成签到,获得积分20
11秒前
11秒前
Super小橘子完成签到,获得积分10
12秒前
12秒前
12秒前
北北北完成签到,获得积分10
12秒前
万能图书馆应助MaxWong采纳,获得10
12秒前
神猪无敌完成签到,获得积分10
13秒前
小祺发布了新的文献求助10
13秒前
英俊的铭应助bobochi采纳,获得10
13秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 360
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3971216
求助须知:如何正确求助?哪些是违规求助? 3515911
关于积分的说明 11180016
捐赠科研通 3251003
什么是DOI,文献DOI怎么找? 1795626
邀请新用户注册赠送积分活动 875937
科研通“疑难数据库(出版商)”最低求助积分说明 805207