亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

The relationship between type, timing and duration of exposure to adverse childhood experiences and adolescent self‐harm and depression: findings from three UK prospective population‐based cohorts

萧条(经济学) 纵向研究 心理学 队列研究 队列 人口 精神科 毒物控制 人口学 医学 临床心理学 环境卫生 内科学 经济 社会学 病理 宏观经济学
作者
Bushra Farooq,Abigail Emma Russell,Laura D Howe,Annie Herbert,Andrew Smith,Helen L. Fisher,Jessie R. Baldwin,Louise Arseneault,Andrea Danese,Becky Mars
出处
期刊:Journal of Child Psychology and Psychiatry [Wiley]
卷期号:65 (10): 1369-1387 被引量:2
标识
DOI:10.1111/jcpp.13986
摘要

Background Adverse childhood experiences (ACEs) are well‐established risk factors for self‐harm and depression. However, despite their high comorbidity, there has been little focus on the impact of developmental timing and the duration of exposure to ACEs on co‐occurring self‐harm and depression. Methods Data were utilised from over 22,000 children and adolescents participating in three UK cohorts, followed up longitudinally for 14–18 years: the Avon Longitudinal Study of Parents and Children (ALSPAC), the Millennium Cohort Study (MCS) and the Environmental Risk (E‐Risk) Longitudinal Twin Study. Multinomial logistic regression models estimated associations between each ACE type and a four‐category outcome: no self‐harm or depression, self‐harm alone, depression alone and self‐harm with co‐occurring depression. A structured life course modelling approach was used to examine whether the accumulation (duration) of exposure to each ACE, or a critical period (timing of ACEs) had the strongest effects on self‐harm and depression in adolescence. Results The majority of ACEs were associated with co‐occurring self‐harm and depression, with consistent findings across cohorts. The importance of timing and duration of ACEs differed across ACEs and across cohorts. For parental mental health problems, longer duration of exposure was strongly associated with co‐occurring self‐harm and depression in both ALSPAC (adjusted OR: 1.18, 95% CI: 1.10–1.25) and MCS (1.18, 1.11–1.26) cohorts. For other ACEs in ALSPAC, exposure in middle childhood was most strongly associated with co‐occurring self‐harm and depression, and ACE occurrence in early childhood and adolescence was more important in the MCS. Conclusions Efforts to mitigate the impact of ACEs should start in early life with continued support throughout childhood, to prevent long‐term exposure to ACEs contributing to risk of self‐harm and depression in adolescence.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Ava应助飞翔的企鹅采纳,获得10
14秒前
22秒前
量子星尘发布了新的文献求助10
29秒前
30秒前
noob_发布了新的文献求助20
31秒前
36秒前
43秒前
noob_完成签到,获得积分20
49秒前
echo发布了新的文献求助10
50秒前
founder发布了新的文献求助20
1分钟前
1分钟前
飞翔的企鹅完成签到,获得积分10
1分钟前
1分钟前
MchemG应助科研通管家采纳,获得10
1分钟前
MchemG应助科研通管家采纳,获得10
1分钟前
量子星尘发布了新的文献求助10
2分钟前
从容的水壶完成签到 ,获得积分10
2分钟前
量子星尘发布了新的文献求助10
3分钟前
George完成签到,获得积分10
3分钟前
4分钟前
wang完成签到,获得积分10
4分钟前
欣欣完成签到 ,获得积分10
4分钟前
柳行天完成签到 ,获得积分10
5分钟前
量子星尘发布了新的文献求助10
5分钟前
5分钟前
Djnsbj发布了新的文献求助10
6分钟前
sinan发布了新的文献求助10
6分钟前
WerWu完成签到,获得积分10
6分钟前
7分钟前
7分钟前
7分钟前
科研通AI2S应助科研通管家采纳,获得10
7分钟前
量子星尘发布了新的文献求助10
7分钟前
7分钟前
dara997发布了新的文献求助10
7分钟前
dara997完成签到,获得积分10
7分钟前
辣椒油完成签到,获得积分20
7分钟前
8分钟前
8分钟前
8分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976665
求助须知:如何正确求助?哪些是违规求助? 3520770
关于积分的说明 11204794
捐赠科研通 3257528
什么是DOI,文献DOI怎么找? 1798733
邀请新用户注册赠送积分活动 877897
科研通“疑难数据库(出版商)”最低求助积分说明 806629