The relationship between type, timing and duration of exposure to adverse childhood experiences and adolescent self‐harm and depression: findings from three UK prospective population‐based cohorts

萧条(经济学) 纵向研究 心理学 队列研究 队列 人口 精神科 毒物控制 人口学 医学 临床心理学 环境卫生 内科学 经济 社会学 病理 宏观经济学
作者
Bushra Farooq,Abigail Emma Russell,Laura D Howe,Annie Herbert,Andrew Smith,Helen L. Fisher,Jessie R. Baldwin,Louise Arseneault,Andrea Danese,Becky Mars
出处
期刊:Journal of Child Psychology and Psychiatry [Wiley]
卷期号:65 (10): 1369-1387 被引量:2
标识
DOI:10.1111/jcpp.13986
摘要

Background Adverse childhood experiences (ACEs) are well‐established risk factors for self‐harm and depression. However, despite their high comorbidity, there has been little focus on the impact of developmental timing and the duration of exposure to ACEs on co‐occurring self‐harm and depression. Methods Data were utilised from over 22,000 children and adolescents participating in three UK cohorts, followed up longitudinally for 14–18 years: the Avon Longitudinal Study of Parents and Children (ALSPAC), the Millennium Cohort Study (MCS) and the Environmental Risk (E‐Risk) Longitudinal Twin Study. Multinomial logistic regression models estimated associations between each ACE type and a four‐category outcome: no self‐harm or depression, self‐harm alone, depression alone and self‐harm with co‐occurring depression. A structured life course modelling approach was used to examine whether the accumulation (duration) of exposure to each ACE, or a critical period (timing of ACEs) had the strongest effects on self‐harm and depression in adolescence. Results The majority of ACEs were associated with co‐occurring self‐harm and depression, with consistent findings across cohorts. The importance of timing and duration of ACEs differed across ACEs and across cohorts. For parental mental health problems, longer duration of exposure was strongly associated with co‐occurring self‐harm and depression in both ALSPAC (adjusted OR: 1.18, 95% CI: 1.10–1.25) and MCS (1.18, 1.11–1.26) cohorts. For other ACEs in ALSPAC, exposure in middle childhood was most strongly associated with co‐occurring self‐harm and depression, and ACE occurrence in early childhood and adolescence was more important in the MCS. Conclusions Efforts to mitigate the impact of ACEs should start in early life with continued support throughout childhood, to prevent long‐term exposure to ACEs contributing to risk of self‐harm and depression in adolescence.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
雪白鸿涛完成签到,获得积分10
刚刚
刚刚
March完成签到,获得积分10
刚刚
十四完成签到 ,获得积分10
1秒前
kakak完成签到,获得积分10
1秒前
张琪琦完成签到,获得积分10
2秒前
XiYang完成签到,获得积分10
2秒前
2秒前
吃鱼的猫完成签到,获得积分10
3秒前
公冶愚志发布了新的文献求助10
3秒前
5秒前
l玖发布了新的文献求助10
5秒前
震动的化蛹完成签到,获得积分20
6秒前
chang_top应助17self采纳,获得10
8秒前
8秒前
乖猫要努力应助明理丹云采纳,获得10
8秒前
小强完成签到,获得积分10
9秒前
科研通AI2S应助超靓诺言采纳,获得10
9秒前
鲈鱼发布了新的文献求助10
9秒前
10秒前
sun发布了新的文献求助10
10秒前
10秒前
10秒前
th完成签到,获得积分10
11秒前
深情安青应助冯冯采纳,获得10
12秒前
坚果发布了新的文献求助10
12秒前
12秒前
元谷雪发布了新的文献求助10
13秒前
13秒前
Akim应助寻找采纳,获得10
13秒前
已绕晕发布了新的文献求助10
14秒前
14秒前
芋泥猫猫丸完成签到 ,获得积分10
14秒前
ding应助科研通管家采纳,获得10
15秒前
852应助科研通管家采纳,获得10
15秒前
joker发布了新的文献求助10
15秒前
15秒前
赘婿应助科研通管家采纳,获得10
15秒前
15秒前
科研通AI2S应助科研通管家采纳,获得10
15秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 360
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3971216
求助须知:如何正确求助?哪些是违规求助? 3515911
关于积分的说明 11180016
捐赠科研通 3251003
什么是DOI,文献DOI怎么找? 1795626
邀请新用户注册赠送积分活动 875937
科研通“疑难数据库(出版商)”最低求助积分说明 805207