[Self-reported quality of life in patients with coronary heart disease and analysis of the associated factors].

Objective: To investigate the quality of life and associated factors in patients with coronary heart disease (CHD) in China. Methods: A cross-sectional study of 25 provinces and cities in China was performed from June to September 2020. A questionnaire was used to collect the socio-demographic and clinical information of patients with CHD, while the European Five-dimensional Quality of Life Scale (EQ-5D) was used to assess the quality of life. Multiple linear regression model was performed to analyze the associated factors. Results: The median age of the 1 075 responders was 60 (52, 67) years, and 797 (74.1%) were men. The EQ-5D and EQ-VAS indices were 0.7 (0.5, 0.8) and 60.0 (40.0, 80.0). Among the five dimensions in the quality of life scale, the frequency of anxiety/depression was the highest (59.8%), while problems in self-care was the lowest (35.8%). In the multiple linear regression model, female, increasing age, obesity, comorbidity(ies), anxiety/depression, social media channels, and receiving the CABG therapy were associated with the lower EQ-5D index (all P<0.05). In addition, increasing age, obesity, comorbidity (ies), depression, anxiety and depression, social media channels, and receiving the CABG therapy were associated with lower EQ-VAS index (all P<0.05). Conclusion: Over half of the patients with CHD in China have a low quality of life, which is related to gender, age, obesity, treatment pathway, the presence or absence of comorbidity (ies), and psychological state. In addition to managing the adverse effects of traditional socio-demographic factors on the quality of life, clinical practices should pay attention to the psychological state of patients. Moreover, establishing a WeChat group for doctor-patient communication could improve the quality of life of CHD patients.目的： 了解我国冠心病患者生活质量并分析其影响因素。 方法： 在2020年6月至9月对我国25个省市的冠心病患者进行横断面研究，使用问卷收集冠心病患者的一般资料，欧洲五维健康量表（EQ-5D）调查患者生活质量，多元线性回归探讨影响生活质量的因素。 结果： 共回收符合要求的调研问卷1 075份，中位年龄60（52，67）岁，男性占74.1%（797例）。总人群EQ-5D指数中位得分0.7（0.5，0.8）；EQ-视觉模拟量表（VAS）中位得分60.0（40.0，80.0）。在五个维度中，报告焦虑/抑郁的比例最高，为59.8%，自我照顾问题的比例最低，为35.8%。多元线性回归显示，女性、中老年、肥胖、有合并症、有焦虑抑郁、社交媒体渠道、冠状动脉旁路移植（CABG）治疗与EQ-5D评分呈负关联（均P<0.05）；老年、有合并症、有抑郁、焦虑合并抑郁、社交媒体渠道、CABG治疗与EQ-VAS评分呈负关联（均P<0.05）。 结论： 我国冠心病患者一半以上生活质量评分偏低，与性别、年龄、肥胖、治疗方式、有无合并症、情绪状态有关。临床除关注传统社会人口学因素对生活质量的不良影响，也应多关注患者心理状态。同时，医患交流群可改善冠心病患者生活质量。.