医学
计时型
傍晚
早晨
加药
队列研究
队列
内科学
物理
天文
作者
Filippo Pigazzani,Kenneth A. Dyar,S. V. Morant,Céline Vetter,Amy Rogers,Robert Flynn,David Rorie,Isla S. Mackenzie,Francesco P. Cappuccio,Roberto Manfredini,Thomas M. MacDonald
标识
DOI:10.1016/j.eclinm.2024.102633
摘要
Timing drug administration to endogenous circadian rhythms may enhance treatment efficacy. In the Chronotype sub-study of the Treatment in Morning versus Evening (TIME) clinical trial we examined whether timing of usual antihypertensive medications according to patient chronotype (a behavioural marker of personal circadian rhythm) may influence clinical cardiovascular outcomes.
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