Diabetes Mellitus Increases the Risk of Apical Periodontitis in Endodontically-Treated Teeth: A Meta-Analysis from 15 Studies

医学 荟萃分析 牙周炎 牙科 糖尿病 内科学 口腔正畸科 内分泌学
作者
Xinyue Liu,Guoping He,Zheng-Jie Qiu,Feng Chen,Jiapeng Wang,Zhigao Huang,Pengtao Zhang,Jian Zhang,Zhong Liu,Cheng Ding,Xing Chen
出处
期刊:Journal of Endodontics [Elsevier BV]
卷期号:49 (12): 1605-1616 被引量:3
标识
DOI:10.1016/j.joen.2023.07.016
摘要

At present, the incidence of diabetes mellitus (DM) is gradually increasing globally. In clinical practice, many patients with diabetes with apical periodontitis (AP) have poor and slow healing of periapical lesions. However, the potential relationship between the 2 is still unclear and controversial. The consensus is that DM can be deemed a risk factor for AP in endodontically-treated teeth. Therefore, we pooled existing studies and carried out a meta-analysis to explore the potential association between the 2.Studies that met the inclusion criteria were selected from the database, and relevant data were extracted. Stata SE 17.0 software was used to analyze the relevant data, and the Newcastle-Ottawa Scale was used to assess the literature's quality. The pooled odds ratio (OR) with a 95% confidence interval (CI) was used to determine the strength of the association between DM and the prevalence of AP after root canal treatment (RCT).After searching, 262 relevant studies were retrieved, fifteen of which met the inclusion criteria. A total of 1087 patients with 2226 teeth were included in this meta-analysis. According to the findings, diabetics showed a higher prevalence of AP after RCT than controls at the tooth level (OR = 1.51, 95% CI = 1.22-1.87, P < .01). At the patient level, DM increased the probability of developing AP in RCT teeth more than 3 times (OR = 3.38, 95% CI = 1.65-6.93, P < .01). Additionally, subgroup analysis was performed by blood glucose status, preoperative AP, and study design. Except for the status of blood glucose, the results were significant in the other 2 groups (P < .05).Available scientific evidence suggests that DM may increase the risk of AP in endodontically-treated teeth. In teeth with preoperative AP, DM might promote the development of AP.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
1秒前
1秒前
1秒前
Ava应助高高的石头采纳,获得10
3秒前
3秒前
飘逸的吐司完成签到 ,获得积分10
4秒前
5秒前
5秒前
6秒前
量子星尘发布了新的文献求助10
6秒前
善学以致用应助tk采纳,获得10
7秒前
8秒前
qqqq完成签到,获得积分10
8秒前
9秒前
zxt完成签到 ,获得积分10
10秒前
MY发布了新的文献求助10
10秒前
思源应助失眠的雁芙采纳,获得10
11秒前
13秒前
14秒前
dong应助wyf采纳,获得10
14秒前
16秒前
逸鑫林完成签到 ,获得积分10
16秒前
16秒前
18秒前
21秒前
唐禹嘉完成签到 ,获得积分10
21秒前
无算浮白发布了新的文献求助10
21秒前
21秒前
Lyuhng+1发布了新的文献求助10
22秒前
24秒前
25秒前
Hello应助errui采纳,获得10
26秒前
葡萄完成签到,获得积分10
27秒前
zzz发布了新的文献求助10
28秒前
Leukocyte完成签到 ,获得积分10
28秒前
MaFY完成签到,获得积分10
30秒前
烟花应助zzk采纳,获得10
30秒前
小高宽度发布了新的文献求助10
31秒前
31秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976177
求助须知:如何正确求助?哪些是违规求助? 3520366
关于积分的说明 11202970
捐赠科研通 3256899
什么是DOI,文献DOI怎么找? 1798535
邀请新用户注册赠送积分活动 877725
科研通“疑难数据库(出版商)”最低求助积分说明 806516