Transition Metal‐Catalyzed Dual C−H Activation/Annulation Reactions Involving Internal Alkynes

Abstract Recently, transition metal‐catalyzed ortho ‐C−H bond activation/annulations involving two internal alkyne molecules have been extensively used to synthesize highly substituted polycyclic aromatic scaffolds. Such reactions have emerged as a powerful atom and step‐economical strategy for the assembly of multifunctional bioactive molecules. In this context, we focused on the recent achievements of dual C−H bond activation/annulations, as well as functionalization reactions involving diaryl/alkyl alkynes.