Significant Correlates of Nocturnal Hypertension in Patients With Hypertension Who Are Treated With Antihypertensive Drugs

医学 夜行的 抗高血压药 内科学 血压 隐匿性高血压 心脏病学 动态血压
作者
Tatsuya Maruhashi,Yoshihiko Kinoshita,Ryoji Ozono,Mitsuaki Nakamaru,Masanori Ninomiya,Jiro Oiwa,Takuji Kawagoe,Osamu Yoshida,Toshiyuki Matsumoto,Yasuo Fukunaga,Kotaro Sumii,Hironori Ueda,Nobuo Shiode,Kosuke Takahari,Yasuhiko Hayashi,Yujiro Ono,Yukiko Nakano,Masakazu Takahashi,Yasuki Kihara,Yukihito Higashi
出处
期刊:American Journal of Hypertension [Oxford University Press]
卷期号:36 (6): 287-296 被引量:3
标识
DOI:10.1093/ajh/hpad014
摘要

Abstract Background Nocturnal hypertension assessed by a home blood pressure monitoring (HBPM) device is associated with an increased risk of cardiovascular events. However, it is still difficult to assess nighttime blood pressure (BP) frequently. The purpose of this cross-sectional study was to identify significant correlates of nocturnal hypertension assessed by an HBPM device in patients with hypertension who are treated with antihypertensive drugs. Methods We measured nighttime BP, morning BP, and evening BP by an HBPM device for 7 consecutive days in 365 medicated patients with hypertension. Results Of the 365 subjects, 138 (37.8%) had nocturnal hypertension defined as a mean nighttime systolic BP of ≥ 120 mm Hg. Receiver operating characteristic curve analyses showed that the diagnostic accuracy of morning systolic BP for subjects with nocturnal hypertension was significantly superior to that of evening systolic BP (P = 0.04) and that of office systolic BP (P < 0.001). Multivariate analysis revealed that morning systolic BP of 125–<135 mm Hg (odds ratio [OR], 2.26; 95% confidence interval [CI], 1.13–4.58; P = 0.02), morning systolic BP of ≥ 135 mm Hg (OR, 16.4; 95% CI, 8.20–32.7; P < 0.001), and a history of cerebrovascular disease (OR, 3.99; 95% CI, 1.75–9.13; P = 0.001) were significantly associated with a higher risk of nocturnal hypertension and that bedtime dosing of antihypertensive drugs was significantly associated with a lower risk of nocturnal hypertension (OR, 0.56; 95% CI, 0.32–0.97; P = 0.04). Conclusions Morning systolic BP of ≥ 125 mm Hg, a history of cerebrovascular disease, and bedtime dosing were significant correlates of nocturnal hypertension in medicated patients with hypertension, and may help detect this risky BP condition. Clinical trials registration University Hospital Medical Information Network Clinical Trials Registry (UMIN000019173).
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
潇湘雪月发布了新的文献求助10
刚刚
故意的靳完成签到,获得积分10
2秒前
mzhmhy完成签到,获得积分10
2秒前
bkagyin应助wish采纳,获得10
6秒前
Afaq发布了新的文献求助10
6秒前
果粒多发布了新的文献求助10
7秒前
7秒前
无辜如容完成签到,获得积分10
8秒前
8秒前
11秒前
12秒前
ASA发布了新的文献求助30
12秒前
13秒前
情怀应助tingting9采纳,获得10
14秒前
FXQ123_范发布了新的文献求助10
14秒前
sun完成签到,获得积分20
14秒前
16秒前
彭于晏应助wldsd采纳,获得30
16秒前
量子星尘发布了新的文献求助10
16秒前
17秒前
17秒前
高一淼发布了新的文献求助10
18秒前
明道若昧完成签到,获得积分10
18秒前
上官若男应助mk采纳,获得10
19秒前
wish完成签到,获得积分10
21秒前
wish发布了新的文献求助10
23秒前
稍等一下完成签到 ,获得积分10
24秒前
momo发布了新的文献求助10
24秒前
26秒前
26秒前
liang白开完成签到,获得积分10
28秒前
mk发布了新的文献求助10
30秒前
丘比特应助嗯嗯采纳,获得10
30秒前
乐乐应助abin采纳,获得10
32秒前
史念薇发布了新的文献求助10
32秒前
32秒前
Hello应助Afaq采纳,获得10
35秒前
Tourist完成签到 ,获得积分10
37秒前
王路飞发布了新的文献求助10
37秒前
40秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989263
求助须知:如何正确求助?哪些是违规求助? 3531418
关于积分的说明 11253814
捐赠科研通 3270066
什么是DOI,文献DOI怎么找? 1804884
邀请新用户注册赠送积分活动 882084
科研通“疑难数据库(出版商)”最低求助积分说明 809136