肾皮质
医学
肾功能
肾
薄壁组织
皮质(解剖学)
肾髓质
髓质
肾脏疾病
泌尿科
超声波
内科学
病理
解剖
放射科
生物
神经科学
作者
Tomoaki Takata,Masahiko Koda,Takaaki Sugihara,Shinobu Sugihara,Toshiaki Okamoto,Ken‐ichi Miyoshi,Masanori Hodotsuka,Yuki Fujise,Tomomitsu Matono,Jun‐ichi Okano,Keiko Hosho,Takuji Iyama,Takeaki Fukui,Satoshi Fukuda,Chishio Munemura,Hajime Isomoto
摘要
The kidney becomes atrophic in advanced chronic kidney disease, and renal size and parenchymal volume correlate with renal function. However, alterations in renal parenchymal volume have not been adequately studied in terms of the renal cortex and medulla. We investigated the relationship between the changes in the renal cortex and medulla and renal function.Renal ultrasound (US) parameters including renal length, parenchymal thickness, cortical thickness and medullary thickness were assessed in 176 subjects, who were categorized into 4 groups based on the estimated glomerular filtration rate (ml/min/1.73 m2): group 1, ≥ 90; group 2, ≥ 60 but < 90; group 3, ≥ 30 but < 60; and group 4, < 30. Renal US parameters in both kidneys were compared among the 4 groups.We found stepwise associations in renal length, cortical thickness and parenchymal thickness with decreased renal function. Medullary thickness showed no changes among groups 1-3. Multiple linear regression analysis including sex, age and renal US parameters showed that only renal length was an independent predictor of renal function. When analyzed in groups 1-3, cortical thickness was the strongest associated parameter. Lower cortical left/right ratio (left cortical thickness/right cortical thickness) showed a stepwise association with a decrease in renal function.Renal length and cortical thickness measured by US were correlated with renal function. In particular, left cortical thickness could help to detect early changes in renal function.
科研通智能强力驱动
Strongly Powered by AbleSci AI