医学
入射(几何)
危险系数
累积发病率
比例危险模型
人口学
心血管健康
置信区间
理想(伦理)
流行病学
队列
疾病
环境卫生
内科学
认识论
光学
物理
哲学
社会学
作者
Shouling Wu,Zhengrong Huang,Xinchun Yang,Yong Zhou,Anxing Wang,Li Chen,Haiyan Zhao,Chunyu Ruan,Yuntao Wu,Aijun Xin,Kuibao Li,Cheng Jin,Jun Cai
出处
期刊:Circulation-cardiovascular Quality and Outcomes
[Ovid Technologies (Wolters Kluwer)]
日期:2012-07-01
卷期号:5 (4): 487-493
被引量:352
标识
DOI:10.1161/circoutcomes.111.963694
摘要
Background— The American Heart Association Committee recently developed definitions of “ideal,” “intermediate,” and “poor” cardiovascular health based on 7 cardiovascular disease (CVD) risk factors or health behaviors. This study evaluated the prevalence of “ideal” American Heart Association cardiovascular health metrics from June 2006 to October 2007 in the Kailuan cohort (n=101 510; age 18–98 years) in northern China and its relationship with the 4-year CVD incidence. Methods and Results— We used Cox proportional hazards regression to calculate hazard ratios and 95% confidence intervals for baseline health behaviors and risk factor categories. The majority of participants (63 676; 69.45%) presented with ≤3 ideal cardiovascular health metrics, whereas 8342 participants (9.1%) had 5 to 7 ideal metrics. Only 93 of 91 698 participants (0.1%) had all 7 metrics in the ideal range. There was a strong relationship between the cumulative incidence of CVD events in the 4-year follow-up and the number of ideal health metrics at baseline; the 1111 participants with 6 and 7 ideal metrics had a significantly lower cumulative incidence of CVD than subjects with no or only 1 ideal health metric (0.8% versus 3.3%). Men had higher rates of CVD events than women (2.46% versus 1.18%). Conclusions— Few adults had ideal cardiovascular health according to the modified American Heart Association definition. We detected a strong inverse relationship between the cumulative CVD incidence and the number of ideal health metrics at baseline. Population-wide prevention, especially lifestyle improvement, is critical to increase the low-risk prevalence and thereafter decrease CVD events. Clinical Trial Registration— URL: http://www.chictr.org/cn/proj/show.aspx?proj=1441 . Unique identifier: ChiCTR-TNC-11001489.
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