Prevalence and Characteristics of Adrenal Tumors in an Unselected Screening Population

医学 原发性醛固酮增多症 腺瘤 人口 肾上腺皮质腺瘤 肾上腺腺瘤 恶性肿瘤 内科学 嗜铬细胞瘤 内分泌系统 生理学 醛固酮 激素 环境卫生
作者
Ying Jing,Jinbo Hu,Rong Luo,Yun Mao,Zhixiao Luo,Mingjun Zhang,Jun Yang,Ying Song,Zhengping Feng,Zhihong Wang,Qingfeng Cheng,Linqiang Ma,Yi Yang,Zhong Li,Zhipeng Du,Yue Wang,Ting Luo,Wenwen He,Yue Sun,Fajin Lv,Qifu Li,Shumin Yang
出处
期刊:Annals of Internal Medicine [American College of Physicians]
卷期号:175 (10): 1383-1391 被引量:46
标识
DOI:10.7326/m22-1619
摘要

With the widespread use of advanced imaging technology, adrenal tumors are increasingly being identified.To investigate the prevalence and characteristics of adrenal tumors in an unselected screening population in China.Cross-sectional study. (ClinicalTrials.gov: NCT04682938).A health examination center in China.Adults having an annual checkup were invited to be screened for adrenal tumors by adrenal computed tomography.The participants with adrenal tumors had further evaluation for malignancy risk and adrenal function.A total of 25 356 participants were screened, 351 of whom were found to have adrenal tumors, for a prevalence of 1.4%. The prevalence increased with age, from 0.2% in participants aged 18 to 25 years to 3.2% in those older than 65 years. Among 351 participants with adrenal tumors, 337 were diagnosed with an adrenocortical adenoma, 14 with another benign nodule, and none with a malignant mass. In 212 participants with an adenoma who completed endocrine testing, 69.3% were diagnosed with a nonfunctioning adenoma, 18.9% with cortisol autonomy, 11.8% with primary aldosteronism, and none with pheochromocytoma. Proportions of nonfunctioning adenomas were similarly high in various age groups (72.2%, 67.8%, and 72.2% in those aged <46, 46 to 65, and ≥66 years, respectively).Only 212 of 337 participants with an adrenocortical adenoma had endocrine testing.The prevalence of adrenal tumors in the general adult screening population is 1.4%, and most of these tumors are nonfunctioning regardless of patient age. Cortisol and aldosterone secretion are the main causes of functional adenomas.National Key Research and Development Program of China and National Natural Science Foundation of China.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
林沐发布了新的文献求助10
1秒前
3秒前
lxf发布了新的文献求助10
3秒前
科研小马应助高兴的猫咪采纳,获得10
4秒前
小钱钱完成签到,获得积分10
5秒前
咪呀完成签到,获得积分10
5秒前
小北完成签到,获得积分10
6秒前
岳苏佳发布了新的文献求助30
6秒前
8秒前
9秒前
隐形曼青应助阿潇采纳,获得10
9秒前
汉堡包应助孤独靖柏采纳,获得10
10秒前
AlexLam完成签到,获得积分10
10秒前
姜维完成签到,获得积分10
10秒前
11秒前
微光发布了新的文献求助10
11秒前
星期八完成签到,获得积分10
12秒前
多多发布了新的文献求助10
12秒前
13秒前
北秋完成签到,获得积分10
13秒前
深情安青应助lily采纳,获得10
13秒前
搞怪哑铃发布了新的文献求助10
13秒前
14秒前
1243437374发布了新的文献求助10
15秒前
15秒前
英俊的铭应助林沐采纳,获得10
15秒前
所所应助科研通管家采纳,获得10
15秒前
无花果应助科研通管家采纳,获得10
16秒前
思源应助科研通管家采纳,获得10
16秒前
爆米花应助科研通管家采纳,获得10
16秒前
ding应助科研通管家采纳,获得10
16秒前
脑洞疼应助科研通管家采纳,获得10
16秒前
不学无术发布了新的文献求助10
17秒前
今后应助Jqq采纳,获得10
18秒前
19秒前
19秒前
dudu发布了新的文献求助10
20秒前
FashionBoy应助搞怪哑铃采纳,获得20
21秒前
叫兽完成签到,获得积分10
22秒前
高分求助中
The ACS Guide to Scholarly Communication 2500
Microlepidoptera Palaearctica, Volumes 1 and 3 - 13 (12-Volume Set) [German] 1122
PraxisRatgeber Mantiden., faszinierende Lauerjäger. – Buch gebraucht kaufen 700
Mantiden - Faszinierende Lauerjäger – Buch gebraucht kaufen 700
Ожившие листья и блуждающие цветы. Практическое руководство по содержанию богомолов [Alive leaves and wandering flowers. A practical guide for keeping praying mantises] 500
Development of a new synthetic process for the synthesis of (S)-methadone and (S)- and (R)-isomethadone as NMDA receptor antagonists for the treatment of depression 500
A Dissection Guide & Atlas to the Rabbit 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3093988
求助须知:如何正确求助?哪些是违规求助? 2745878
关于积分的说明 7587633
捐赠科研通 2397197
什么是DOI,文献DOI怎么找? 1271798
科研通“疑难数据库(出版商)”最低求助积分说明 615272
版权声明 598844