丝素
即时
材料科学
纳米技术
粘附
止血剂
生物医学工程
化学工程
丝绸
复合材料
止血
医学
外科
化学
食品科学
工程类
作者
Aizhen Geng,Yuting Luo,Minzhang Zheng,Jie Zheng,Rui Zhu,Shumeng Bai
摘要
Powder-based hemostatic technology has offered unprecedented opportunities in surgical sealing and repair of irregularly shaped and noncompressible wounds. Despite their routine use, existing clinical hemostatic powders are challenged either by poor mechanical properties or inadequate adhesion to bleeding tissues in biological environments. Here, inspired by the mussel foot proteins' fusion assembly strategy, a novel silk fibroin-based hemostatic powder (named as SF/PEG/TA) with instant and robust adhesion performance is developed. Upon absorbing interfacial liquids, the SF/PEG/TA powders rapidly swell into micro-gels and subsequently contact with each other to transform into a macroscopically homogeneous hydrogel
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