医学
糖尿病足
荟萃分析
糖尿病足溃疡
置信区间
优势比
随机对照试验
外科
内科学
糖尿病
内分泌学
作者
Yi Luo,Li Li,Ping Zhao,Chuan Yang,Jun Zhang
出处
期刊:Journal of Wound Care
[Mark Allen Group]
日期:2022-11-02
卷期号:31 (11): 979-986
被引量:5
标识
DOI:10.12968/jowc.2022.31.11.979
摘要
Objective: Silver dressings have been used in the treatment of diabetic foot ulcers (DFUs). However, meta-analyses examining their effectiveness is lacking. Therefore, this meta-analysis evaluates the effectiveness of silver dressings on DFU healing. Method: Various databases were searched for randomised controlled trials (RCTs) of silver dressing applied to DFUs. Results: A total of seven studies involving 650 patients were identified for inclusion in the meta-analysis. The odds ratio (OR) for silver dressing improving wound healing rate, complete healing time, ulcer-related in-hospital time and infection resolution rate were: 4.02 (95% confidence interval [CI]: 2.25–7.17; p<0.01); 2.81 (95% CI: –3.33––2.29; p<0.01); 12.13 (95% CI:–20.64––3.62; p<0.01); and 7.36 (95% CI: 1.58–34.22; p=0.01), respectively. The OR on ulcer area reduction was 8.60 (95% CI:–8.93–26.12; p=0.34) indicating no significant effect. Conclusion: The results of this meta-analysis showed that silver dressings enhance DFU healing rate, shorten the time to complete healing, shorten in-hospital duration, and improve infection resolution rate, while having no significant effect on reduction of ulcer area. Large-scale, multicentre, rigorously designed RCTs are recommended for future investigation to justify the beneficial effects of silver dressings on DFU healing.
科研通智能强力驱动
Strongly Powered by AbleSci AI