Intraoperative Coagulation Monitoring in Liver Transplant Surgery

Coagulation occurs in three phases such as primary haemostasis, coagulation and fibrinolysis, and liver dysfunction affects all three functions [1]. The liver is responsible for the synthesis of all clotting factors (except von Willebrand factor—vWf), all anticoagulants, as well as production of fibrinolytic proteins [2], and therefore haemostasis abnormality in liver disease is multifactorial—Box 18.1.