The chemical components of the family Gesneriaceae are complex and diverse.The compounds isolated from the plants of this family mainly include flavonoids, phenylethanoid glycosides, terpenoids, anthraquinones, organic carboxylic acids, and steroids.Gesneriaceae have a wide range of pharmacological activities, including antioxidant, antibacterial, anti-tumor, enzyme inhibition and activation, cytotoxicity, and anti-Alzheimer activities.In this study, the chemical components and pharmacological activities of Gesneriaceae in recent years were summarized to provide a reference for future studies.