胶质母细胞瘤
癌症研究
效力
肿瘤细胞
化学
生物
体外
生物化学
作者
Dongrui Wang,Renate Starr,Wen-Chung Chang,Brenda Aguilar,Darya Alizadeh,Sarah Wright,Xin Yang,Alfonso Brito,Aniee Sarkissian,Julie R. Ostberg,Li Li,Yanhong Shi,Margarita Gutova,Karen S. Aboody,Behnam Badie,Stephen J. Forman,Michael E. Barish,Christine E. Brown
出处
期刊:Science Translational Medicine
[American Association for the Advancement of Science (AAAS)]
日期:2020-03-04
卷期号:12 (533)
被引量:175
标识
DOI:10.1126/scitranslmed.aaw2672
摘要
CAR T cells using chlorotoxin as the tumor-targeting domain recognize and kill glioblastoma with high specificity and potency.
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