Immobilization of glucose oxidase enzyme on NiAl-LDHs for application in microfluidic fuel cell and serotonin detection.

Abstract In this work, an enzymatic glucose oxidase (GOx) electrode immobilized on double layered hydroxides of NiAl (NiAl-LDHs) was developed for the detection of serotonin neurotransmitters that may be present in human blood samples and carry out the glucose oxidation present in this fluid for energy conversion, and can be applied as self-feeding electrodes in Lab-on-a-Chip devices. The self-feeding electrodes based on fuel cells have a very promising future in lab-on-a-chip devices because they do not occupy an external power source, their manufacturing processes are relatively simple and low cost, and can be developed for different applications such as the determination of biomolecules for diagnosis of various diseases.