Abstract Metal–organic frameworks (MOFs) possess the advantages of tailorable porosity, adjustable composition, and tunable topologies and are considered promising precursors and self‐templates for the synthesis of complex nanostructures as advanced electrode materials for energy storage. Among various strategies, wet‐chemical method endows better control over topological evolution and compositional transformation of MOF crystals. Herein, the authors comprehensively review the recent achievements on wet‐chemical derivation of MOF via etching, ion‐exchange, hydrolysis, and chemical transformation, underscore the corresponding mechanisms, and highlight their important applications in supercapacitors and secondary batteries.