Studies on the Chemical Constituents of Secondary Metabolites of Marine-derived Aspergillus fumigatus(II)

To study the secondary metabolites from the fermentation of Aspergillus fumigatus,column chromatography was used to separate and purify constituents.During the process,the structure of the constituents was elucidated by MS、NMR spectral data and physiochemical properties.Eight compounds were isolated and identified as cyclo-(Ala-Val)(1),cyclo-L-tryptophyl-L-proline(2),N-acetyltyltyrsmine(3),2-(4-hydroxyphenyl)-acetamide(4),isosclerone(5),protocatechuli acid methyl ester(6),ergosterol(7) and ergosterol peroxide(8),respectively,and all the compounds were extracted from Aspergillus fumigatus for the first time.