Ni(OH)2-MoS2 Nanocomposite Modified Glassy Carbon Electrode for the Detection of Dopamine and α-Lipoic Acid

Here, we report an electrochemical sensor realized using a nanocomposite consisting of nickel hydroxide nanosheets and exfoliated MoS 2 nanosheets. The system was able to detect dopamine and α -lipoic acid in phosphate-buffered saline (PBS) solution at a pH of 7.4. The nanocomposites were characterized using microscopic and spectroscopic methods. The electrochemical characterizations were carried out using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and differential pulse voltammetry (DPV). It was observed that Ni(OH) 2 /MoS 2 composite in the weight ratio of 2:1 has better results in terms of electrochemically active surface area, impedance, analytical parameters and stability. The dynamic range for dopamine detection was 0.75 − 95 μ M with a LOD value of 56 nM and for α -lipoic acid, the range was 1 − 75 μ M and the LOD was 51 nM.