Landiolol for perioperative atrial tachyarrhythmias in cardiac and thoracic surgery patients: a systematic review and meta-analysis

Editor—Atrial tachyarrhythmias are common complications of cardiac and thoracic surgeries. 1 McIntyre W.F. Post-operative atrial fibrillation after cardiac surgery: challenges throughout the patient journey. Front Cardiovasc Med. 2023; 101156626 Google Scholar ,2 Eikelboom R. Sanjanwala R. Le M.L. Yamashita M.H. Arora R.C. Postoperative atrial fibrillation after cardiac surgery: a systematic review and meta-analysis. Ann Thorac Surg. 2021; 111: 544-554 Google Scholar We performed a systematic review and meta-analysis to collate and assess the available evidence on the safety and efficacy of landiolol, a short-acting intravenous cardioselective beta1 receptor antagonist, for treating perioperative atrial tachyarrhythmias in this population. The full details of the study are available in a registered protocol (PROSPERO: CRD42023391905). Additions to the protocol appear in Supplementary Appendix A1.