粘液
粘蛋白
生物
肠道菌群
低聚糖
蛋白质组
肥胖
微生物群
作文(语言)
内分泌学
生理学
内科学
免疫学
生物化学
医学
语言学
生态学
生物信息学
哲学
作者
Paola Paone,Dimitrios Latousakis,Romano Terrasi,Didier Vertommen,Ching Jian,Valentina Borlandelli,Francesco Suriano,Malin Johansson,Anthony Puel,Caroline Bouzin,Nathalie M. Delzenne,Anne Salonen,Nathalie Juge,Bogdan I. Florea,Giulio G. Muccioli,Herman S. Overkleeft,Matthias Van Hul,Patrice D. Cani
出处
期刊:Gut
[BMJ]
日期:2024-05-13
卷期号:73 (10): 1632-1649
被引量:2
标识
DOI:10.1136/gutjnl-2023-330301
摘要
To decipher the mechanisms by which the major human milk oligosaccharide (HMO), 2'-fucosyllactose (2'FL), can affect body weight and fat mass gain on high-fat diet (HFD) feeding in mice. We wanted to elucidate whether 2'FL metabolic effects are linked with changes in intestinal mucus production and secretion, mucin glycosylation and degradation, as well as with the modulation of the gut microbiota, faecal proteome and endocannabinoid (eCB) system.
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