Cardiovascular risk in young people with childhood onset systemic lupus erythematosus

Since 1940, epidemiologists, clinicians, and scientists promoted increased awareness of the crucial importance of promoting preventive strategies for minimising the risk of poor health later in life. This is particularly relevant to children and young people with chronic inflammatory diseases, including childhood-onset systemic lupus erythematosus (SLE), which are almost always associated with increased risk of comorbidity. A wealth of literature emphasises the contribution of chronic inflammation to the development of subclinical atherosclerosis, which drives the increased risk of cardiovascular disease, and many guidelines across specialties highlight the need for cardiovascular disease risk stratification and tailored management.