A study has been made on the possibility of friction stir spot welding (FSSW) of the aluminium to copper sheet with SiC nanoparticles. Modified microstructures with different morphologies and properties were observed in the joint interface. It has been shown that the reinforcing particles cause an increasing role in the developed mechanical properties of joint samples such as strength and hardness due to the more particle-stimulated nucleation of recrystallisation (PSN), Zener pinning effect, and larger tension for the movement of dislocations. The experimental measurements indicated that AlCu and Al2Cu were the main intermetallic compounds formed in the interfacial region. It was concluded from fracture surfaces that ductile fracture is the primary fracture mode during the FSSW with SiC reinforcing particles.