医学
微波消融
烧蚀
热烧蚀
回顾性队列研究
超声波
外科
放射科
血肿
甲状腺
射频消融术
内科学
作者
Xiaojing Cao,Ming-An Yu,Zhu Ya-lin,Qi Lu,Zhi-Bin Cong,Guo-Zhen Yan,Juan Liu,Hongling Wang,Geng Liu,Guo JianQin,Ying Hao,Zhonghua Wang,Xue Wang,Jiahui He,Aini Shataer,Xiaofang Liu,Zhenlong Zhao,Ying Wei,Li-Li Peng,Yan Li,Shurong Wang,Ying Che
标识
DOI:10.1080/02656736.2021.1936218
摘要
Purpose Ultrasound-guided thermal ablation (including microwave ablation [MWA] and radiofrequency ablation [RFA]) has emerged as a remarkable technology for the treatment of benign and malignant diseases. The objective of this multicenter study was to assess the efficacy and safety of thermal ablation in a large cohort of patients with papillary thyroid microcarcinoma (PTMC).Materials and methods Retrospective study of 725 patients who underwent MWA/RFA at 11 centers between March 2015 and March 2020. The mean age of patients was 46 ± 11 years (range, 22–81); the mean follow-up time was 21 ± 13 months (range, 6–60). Changes in size of tumor, the rates of tumor disappearance, disease progression, and complications were assessed.Results From 6 months post-ablation, the size of tumors was significantly reduced compared with those recorded pre-ablation (p < 0.001 for all). Five hundred and fifteen (71.0%) PTMCs had completely disappeared as assessed by ultrasound examination. Six (0.8%) patients developed disease progression post-ablation; of these, 5 (0.7%) patients developed new PTMCs, while one (0.1%) patient developed cervical lymph node metastasis. Nineteen (2.6%) patients developed complications post-ablation; of these 14 (1.9%) patients developed voice hoarseness, 4 (0.6%) developed hematoma, and one (0.1%) patient developed cough.Conclusions Ultrasound-guided thermal ablation represents an effective and safe treatment for patients with PTMC besides active surveillance and surgery.
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