[Research progress of the relationship between Candida albicans and dental caries].

Candida albicans (Ca) is an important opportunistic pathogenic fungus found in the oral cavity, which plays an important role in oral microecological balance, and often interacting with other bacteria including Streptococcusmutans (Sm). Meanwhile, the characteristics of Ca such as adhesion, acidogenicity, aciduric nature and the ability to produce collagenolytic proteinases indicate its latent cariogenic potential. This review summarizes the research progress of the detectable rate of Ca in caries, its cariogenic potential and the interaction with Sm and other oral bacteria, in order to extend the understanding of pathogenesis of dental caries and to contribute new therapeutic and preventive strategies for dental caries.白色念珠菌是口腔中重要的机会致病真菌。近年来，研究发现它能与口腔常见致龋菌变异链球菌发生相互作用，对维持口腔正常的微生态平衡具有重要作用；同时白色念珠菌自身具有黏附、产酸、耐酸等作用，能使牙体硬组织脱矿，并能产生胶原蛋白酶降解牙体硬组织的有机质，具有致龋潜能。本文从白色念珠菌在患龋人群中的检出率、致龋潜力、与变异链球菌的交互作用、与其他口腔细菌的交互作用4个方面进行综述，以期拓展对口腔微生物在龋病中作用的认识，为龋病的临床防治提供新思路。.