医学
硬化疗法
头颈部
淋巴系统
外科
畸形
外科切除术
病理
作者
Shengcai Wang,Jun Tai,Jie Zhang,Xin Ni
出处
期刊:PubMed
日期:2019-06-07
卷期号:54 (6): 471-476
标识
DOI:10.3760/cma.j.issn.1673-0860.2019.06.015
摘要
More than seventy percent of lymphatic malformations (LMs) occur in head and neck region. The management of head and neck LMs is challenging,especially for diffuse and infiltrative cases.It can cause deformity and death in severe patients. Surgical resection is the main method to treat LMs in the past and sclerotherapy has also greatly improved the treatment out come of LMs over the past 20 years. However, it is still hardly to achieve satisfactory prognosis for the patients with extensively infiltrative lesions, regardless of surgical resection or sclerotherapy. In the past five years, some scholars have made a preliminary exploration of new treatment methods, such as oral medicine, to diversify the treatment options of head and neck LMs. This article will review the general situation, biological properties, clinical characteristics, diagnostic methods, and current treatment strategies for LMs as well as trends in management of LMs.淋巴管畸形(lymphatic malformations,LM)70%以上发生于头颈部,治疗困难。其中弥漫性浸润性生长的LM治疗更是极具挑战,是致畸、致死的重要原因。手术切除是以往治疗LM的主要手段。近20多年来,硬化剂的使用显著提高了LM的治疗水平,但是对于病变范围大、浸润广的重症患者,无论手术切除还是硬化剂治疗均难以取得满意疗效。近5年来,有学者对口服药物等新治疗方法进行初步探索,使头颈部LM的治疗手段多样化。本文对头颈部LM的概况、生物学性质、临床特点、诊断方法、治疗策略及诊疗发展趋势等进行综述。.
科研通智能强力驱动
Strongly Powered by AbleSci AI