Changes of left atrial function after radiofrequency ablation of frequent premature ventricular contractions from different origins

Objective To evaluate the changes of left atrial function after radiofrequency catheter ablation (RFCA)and the influence of different origin frequent premature ventricular contractions(PVC)on left atrial function before and after RFCA. Methods A total of 68 inpatients with frequent PVC observed on 24 h Holter monitoring(>10 000/24 h)and successful radiofrequency ablation were included in this study in the Second Hospital of Hebei Medical University from December 2014 to December 2015.Among them 41 patients with frequent PVC originated from the right ventricle [age(47±15)years, 15 males] and 27 originated from the left ventricle [age(50±17)years, 16 males]. Left atrial structure and function indices were measured by echocardiography before and after RFCA at 1 day, 2 weeks and 4 weeks to investigate whether there was a difference between groups. Results In the right ventricular PVC group, the left atrium diameter(LAD)showed a little decreasing trend, the LAD at 2 weeks after operation was the lowest level [(31.7±3.6) mm vs.(33.2±4.6) mm, P 0.05). The S and the strain rate at left ventricular diastolic early(SRe)in the right ventricular group was significantly higher than that in the left ventricular group(P 0.05). Conclusions The left atrial function was significantly improved in 4 weeks after operation in the right ventricular origin group, but had no change in the left ventricular origin group.We should make more aggressive treatment of frequent PVC originating from the right ventricle. Key words: Premature ventricular contractions; Radiofrequency catheter ablation; Left atrium; Echocardiography