Application of bevacizumab for malignant brain edema

Anti-angiogenic drugs such as bevacizumab can effectively alleviate the patients′ brain edema and clinical symptoms and improve the patients′ life quality by reducing vascular permeability and the blood-brain barrier damage. Bevacizumab has got positive efficacy in the clinical, so that it is considered as an effective and safe treatment for malignant brain edema. Key words: Vascular endothelial growth factors; Brain edema; Brain neoplasms; Bevacizumab