Synthesis of 2-deoxy-d-glucose coated Fe3O4 nanoparticles for application in targeted delivery of the Pt(iv) prodrug of cisplatin – a novel approach in chemotherapy

Pt(IV) prodrug of cisplatin was loaded on 2DG functionalized silica coated Fe₃O₄ nanoparticles. The formulation alone exhibited biocompatibility whereas Pt(IV) loaded formulation exhibited cytotoxicity comparable with cisplatin.