医学
肺动脉高压
安慰剂
内科学
心脏病学
血管阻力
置信区间
临床终点
不利影响
血压
临床试验
外科
病理
替代医学
作者
Marius M. Hoeper,David B. Badesch,Hossein Ardeschir Ghofrani,J. Simon R. Gibbs,Mardi Gomberg‐Maitland,Vallerie V. McLaughlin,Ioana R. Preston,Rogério Souza,Aaron B. Waxman,Ekkehard Grünig,Grzegorz Kopeć,G. Meyer,Karen M. Olsson,Stephan Rosenkranz,Yayun Xu,B.I. Miller,Marcie Fowler,John Butler,Joerg Koglin,Janethe de Oliveira Pena
标识
DOI:10.1056/nejmoa2213558
摘要
In patients with pulmonary arterial hypertension who were receiving stable background therapy, sotatercept resulted in a greater improvement in exercise capacity (as assessed by the 6-minute walk test) than placebo. (Funded by Acceleron Pharma, a subsidiary of MSD; STELLAR ClinicalTrials.gov number, NCT04576988.).
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