聚己内酯
材料科学
静电纺丝
复合材料
复合数
极限抗拉强度
熔融纺丝
纺纱
纤维
制作
多孔性
纳米-
聚合物
医学
病理
替代医学
作者
Zhijun Chen,Yanbo Liu,Juan Huang,Ming Hao,Xiao Hu,Xiaoming Qian,Jintu Fan,Hongjun Yang,Bo Yang
出处
期刊:Polymers
[MDPI AG]
日期:2022-08-19
卷期号:14 (16): 3404-3404
被引量:10
标识
DOI:10.3390/polym14163404
摘要
In this paper, near-field direct-writing melt electrospinning technology was employed to fabricate a polycaprolactone/nano-hydroxyapatite (PCL/nHA) scaffold for future applications in tissue engineering. The influences of different fabrication parameters on the structural characteristics, mechanical properties, and thermal stability of the scaffolds were discussed. It was found that the moving speed of the receiving plate had the most significant effect on the scaffold performance, followed by the receiving distance and spinning voltage. The results also showed that these process parameters affected the fiber diameter, corresponding coefficient of variation, porosity of the composite scaffolds, and mechanical properties of the samples, including the tensile strength and fiber peeling strength. Moreover, the process parameters could influence the thermal degradation performance and melting process. Although the mass loss of the composite scaffolds was not obvious after degradation, the mechanical performance degraded severely. It was concluded that the more appropriate process parameters for preparing PCL/nHA scaffolds were a spinning voltage of −4 kV, receiving distance of 4 mm, moving speed of receiving plate of 5 mm/s, and melt temperature of 130 °C. This study proved that near-field direct-writing melt electrospinning technology is a good method to obtain PCL/nHA composite scaffolds with an excellent mechanical properties and desired morphology for future tissue engineering applications.
科研通智能强力驱动
Strongly Powered by AbleSci AI