DNA折纸
四方晶系
对称(几何)
DNA纳米技术
各向异性
小角X射线散射
DNA
结晶学
晶体结构
核酸
齐次空间
八面体
化学物理
材料科学
拓扑(电路)
物理
纳米技术
化学
散射
几何学
光学
纳米结构
数学
组合数学
生物化学
作者
Yong Wang,Xuehui Yan,Zhaoyu Zhou,Ningning Ma,Ye Tian
标识
DOI:10.1002/anie.202208290
摘要
Abstract DNA nanotechnology has provided credible approaches for assembly of three‐dimensional (3D) lattices with complex patterns. However, the symmetries are strictly dependent on their initial configurations and difficult to alter via non‐thermal treatments. While switchable nucleic acid structures have been employed to construct deformable DNA motifs, it remains challenging to arrange them anisotropically in 3D lattices to trigger directed collective shape transition and dynamic symmetry conversion. In this work, we used octahedral DNA origami frames to synthesize four DNA origami lattices by placing the pH‐reactive i‐motif sequences in the desired dimensions. Thereinto, lattices with an anisotropic design can switch between simple cubic ( SC ) and simple tetragonal ( ST ) upon pH change. Small angle X‐ray scattering (SAXS) results reveal the feasibility of obtaining 3D lattices with sensitive responses to external stimuli, expanding the way to obtain low‐symmetry lattices.
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