亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

The effect of hinge position on corneal sensation and dry eye after LASIK

角膜刀 医学 激光手术 角膜磨镶术 眼科 角膜 外科 感觉 角膜地形图 生物 神经科学
作者
Eric D. Donnenfeld,Kerry Solomon,Henry D. Perry,Sima J. Doshi,Michael Ehrenhaus,Renée Solomon,Seth A. Biser
出处
期刊:Ophthalmology [Elsevier]
卷期号:110 (5): 1023-1029 被引量:187
标识
DOI:10.1016/s0161-6420(03)00100-3
摘要

To investigate the effect of hinge position on corneal sensation and dry eye syndrome after laser in situ keratomileusis (LASIK).Prospective, randomized, self-controlled trial.Fifty-two patients >/=18 years of age undergoing bilateral LASIK.Patients underwent bilateral LASIK with the superior-hinge Hansatome microkeratome in one eye and the nasal-hinge Amadeus microkeratome in the other eye. In all eyes, the flaps were 160 micro m thick, with a diameter of 9.5 mm.Masked Cochet-Bonnet esthesiometry was performed centrally before surgery and at 1 week, 1 month, 3 months, and 6 months after surgery. Dry eye was evaluated at the same time intervals with lissamine green corneal and conjunctival staining, Schirmer testing with anesthesia, and tear-film breakup time. Subjective evaluation of dry eye sensation was performed at 3 and 6 months after surgery.Corneal sensation was reduced in eyes with either superior- or nasal-hinge corneal flaps at 1 week, 1 month, and 3 months after surgery (P < 0.001). Compared with preoperative values, a significant reduction in corneal sensation remained at 6 months in corneas with superior-hinge flaps (P < 0.001) but not in corneas with nasal-hinge flaps (P = 0.263). Mean corneal sensation was greater in corneas with a nasal-hinge flap compared with corneas with a superior-hinge flap at all postoperative visits (P < 0.001). The loss of sensation was greatest at 1 week and showed improvement at each subsequent time interval up to 6 months. Overall, dry eye signs and symptoms were greatest during the immediate postoperative period and improved at all subsequent time intervals. Dry eye signs and symptoms were generally greatest in the eyes with a superior-hinge flap and milder in eyes with a nasal-hinge flap.The long posterior corneal nerves, which innervate the cornea, enter the eye at 3- and 9-o'clock. A superior-hinge flap transects both arms of the neuroplexus, whereas a nasal hinge transects only the temporal arm. LASIK results in a significant reduction in corneal sensation. Corneal sensation and dry eye signs and symptoms decreased immediately after LASIK and improved at all time periods between 1 week and 6 months in eyes with both a nasal-hinge flap and a superior-hinge flap. However, the loss of corneal sensation and presence of dry eye syndrome were greater in eyes with a superior-hinge flap than in eyes with a nasal-hinge flap.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
布通发布了新的文献求助30
刚刚
陶兜兜完成签到,获得积分10
10秒前
安静的磬发布了新的文献求助10
11秒前
科研通AI2S应助安静的磬采纳,获得10
17秒前
科研通AI2S应助陶兜兜采纳,获得10
35秒前
苗条青槐完成签到 ,获得积分10
37秒前
支觅露完成签到 ,获得积分10
39秒前
CipherSage应助蝈蝈采纳,获得30
55秒前
ooooyasumi完成签到,获得积分10
57秒前
1分钟前
1分钟前
NexusExplorer应助吵吵robot采纳,获得10
1分钟前
1分钟前
姚老表完成签到,获得积分10
1分钟前
1分钟前
LU完成签到 ,获得积分10
1分钟前
2分钟前
2分钟前
bkagyin应助KSung采纳,获得10
2分钟前
体贴问丝完成签到 ,获得积分10
2分钟前
2分钟前
KSung发布了新的文献求助10
3分钟前
桃园奈奈露完成签到,获得积分10
3分钟前
深情安青应助科研通管家采纳,获得10
3分钟前
隐形曼青应助科研通管家采纳,获得10
3分钟前
Jasper应助科研通管家采纳,获得10
3分钟前
英勇背包完成签到,获得积分10
3分钟前
无名完成签到,获得积分10
3分钟前
李健应助bosslin采纳,获得10
3分钟前
务实怀柔完成签到 ,获得积分10
3分钟前
3分钟前
hayek完成签到,获得积分10
4分钟前
4分钟前
布通完成签到,获得积分10
4分钟前
LANGYE发布了新的文献求助10
5分钟前
寻道图强应助科研通管家采纳,获得30
5分钟前
寻道图强应助科研通管家采纳,获得30
5分钟前
蝈蝈发布了新的文献求助30
5分钟前
碧蓝香芦完成签到 ,获得积分10
5分钟前
英勇背包发布了新的文献求助10
5分钟前
高分求助中
Sustainability in Tides Chemistry 1500
Handbook of the Mammals of the World – Volume 3: Primates 805
拟南芥模式识别受体参与调控抗病蛋白介导的ETI免疫反应的机制研究 550
Gerard de Lairesse : an artist between stage and studio 500
Digging and Dealing in Eighteenth-Century Rome 500
Queer Politics in Times of New Authoritarianisms: Popular Culture in South Asia 500
Manual of Sewer Condition Classification 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3068019
求助须知:如何正确求助?哪些是违规求助? 2722010
关于积分的说明 7475912
捐赠科研通 2369097
什么是DOI,文献DOI怎么找? 1256116
科研通“疑难数据库(出版商)”最低求助积分说明 609454
版权声明 596795