生物
动物
病毒学
布尼亚病毒科
病毒
乌鳢科
兽医学
滴答声
医学
硬蜱科
作者
Al'khovskiĭ Sv,L'vov Dk,Shchelkanov MIu,А. М. Щетинин,Deriabin Pg,Samokhvalov Ei,Gitel'man Ak,Botikov Ag
出处
期刊:PubMed
日期:2014-03-20
卷期号:58 (5): 11-5
被引量:10
摘要
The Issyk-Kul virus (etiological agent of the Issyk-Kul fever) was originally isolated from bats (Nyctalus noctula Schreber, 1774 (Chiroptera: Vespertilionidae)) and their parasites ticks (Argas (Carios) vespertilionis Latreille, 1796 (Parasitiformes: Argasidae)) in Kirghizia. Sporadic cases and epidemics of the Issyk-Kul fever are observed in Central Asia since 1979. The ISKV genome was de novo sequenced using the next-generation sequencing technology. According to the molecular-genetic and phylogenetic analysis, the ISKV is a member of a novel group in the genus Nairovirus (Bunyaviridae). Based on the data obtained, molecular-genetic methods can be used for ISKV detection (PCR) for the Issyk-Kul fever monitoring and diagnosis in the endemic areas.
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