形状记忆合金*
咀嚼力
医学
咬合力商
运动范围
弱点
下颌骨(节肢动物口器)
口腔正畸科
外科
生物
数学
植物
组合数学
属
作者
H.W. van Bruggen,Renske I. Wadman,Ewald M. Bronkhorst,Maureen Leeuw,N.H.J. Creugers,Stanimira I. Kalaykova,W. Ludo van der Pol,M.H. Steenks
出处
期刊:Neurology
[Ovid Technologies (Wolters Kluwer)]
日期:2016-02-09
卷期号:86 (6): 552-559
被引量:23
标识
DOI:10.1212/wnl.0000000000002348
摘要
In a cross-sectional study, we aimed to determine (1) the effect of spinal muscular atrophy (SMA) type 2 and 3 on mandibular function reflected as masticatory performance, mandibular range of motion, and bite force and (2) the predictors of mandibular dysfunction.Sixty patients with SMA type 2 and 3 (mean age 32.3 years, SD 17.4 years) and 60 age-matched controls filled out questionnaires about impairments of mandibular function. All participants underwent detailed clinical examination to document the mandibular range of motion including maximal mouth opening, bite force, and masticatory function.All mandibular movements, including mouth opening, lateral range of motion, and protrusion of the mandible, were reduced in patients with SMA type 2 and 3 compared to healthy controls (p < 0.001). Maximal bite force was 19% lower in patients than controls, and more in patients with SMA type 2 than type 3. The strongest predictive factor was SMA type for impairment of mandibular range of motion (R(2) = 0.82) and weakness of neck muscles for bite force (R(2) = 0.47).Reduced mandibular mobility and bite force are common complications in SMA. SMA type and neck muscle strength are important correlates of these complications. We provide further evidence for clinically relevant bulbar involvement in patients with SMA.
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