适体
信号(编程语言)
肉眼
计算机科学
生物传感器
计算机硬件
工作站
可扩展性
纳米技术
嵌入式系统
材料科学
化学
检出限
色谱法
遗传学
生物
操作系统
程序设计语言
作者
Ying Gu,Jinwen Li,Kun Qian,Zhen Zhang,Shuo Wang,Junping Wang
标识
DOI:10.1016/j.snb.2020.127856
摘要
A novel dual-signal sensing system was developed for on-site analysis. A custom-built miniaturized workstation coupled with a home-made magneto-electrochemical detection module was employed for electrochemical sensing. The miniaturized workstation could be controlled by smartphone and all devices and tools in this integrated dual-signal biosensing platform were portable, which applies to on-site analysis. Meanwhile, by simple separation, color responses could be captured by naked-eye observation to detect target even in the absence of any instrument. The differences in target amounts were converted into the color change of AuNPs dispersion and the current change on solid electrode. A particularly objective in developing such versatile dual-signal strategy is to offer an user-friendly, portable, time-saving and cost-effective analysis strategy. The feasibility of the naked-eye colorimetric/magneto-electrochemical biosensing strategy was exemplified by using ATP and Hg2+ as model target. The LOD of two targets in electrochemical unit were 5.203 pmol L−1 and 1.597 pmol L−1 (S/N = 3), respectively. More importantly, the versatile dual-signal platform possesses favorable extensibility and could realize on-demand fast screening of other targets by using appropriate aptamers.
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