医学
不利影响
肺癌
内科学
癌症
免疫疗法
免疫系统
肿瘤科
免疫学
作者
Biagio Ricciuti,Abdul Rafeh Naqash,Brian S. Henick,Deepa Rangachari,Jarushka Naidoo,Deepti Venkatraman,Giuseppe Lamberti,Gonzálo Recondo,J. Zhang,Shravanti Macherla,Sameer Baig,Paul R. Walker,Kartik Sehgal,Renato Umeton,Lynette M. Sholl,Naiyer A. Rizvi,Daniel B. Costa,Mark M. Awad
标识
DOI:10.1016/j.jtho.2019.08.422
摘要
Immune-checkpoint inhibitors (ICIs) have shown promising activity in only a fraction of patients with small cell lung cancer (SCLC), and factors associated with clinical benefit are not well characterized. The development of immune-related adverse events (irAEs) may correlate with benefit from immune checkpoint inhibitors (ICIs) among patients with cancer. Whether an association exists between irAE development and improved clinical outcomes to ICIs in small cell lung cancer (SCLC) is unknown.
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