材料科学
纳米材料
纳米技术
介孔材料
纳米复合材料
化学工程
金属有机骨架
介孔二氧化硅
混合材料
介孔有机硅
多孔性
纳米颗粒
催化作用
复合材料
化学
有机化学
吸附
工程类
作者
Qi Lei,Jimin Guo,Esmeralda Arreguin-Martinez,Jianjun Shi,C. Jeffrey Brinker,Wei Zhu
出处
期刊:ACS applied bio materials
[American Chemical Society]
日期:2021-02-02
卷期号:4 (2): 1221-1228
被引量:5
标识
DOI:10.1021/acsabm.0c01518
摘要
The structural modulation of multicompartment porous nanomaterials is one of the major challenges of nanoscience. Herein, by utilizing the polyhedral effects/characteristics of metal-organic frameworks (MOFs), we present a versatile approach to construct MOF-organosilica hybrid branched nanocomposites with MOF cores, SiO2 shells, and periodic mesoporous organosilica (PMO) branches. The morphology, structure, and functions of the obtained hybrid nanocomposites can be facilely modulated by varying particle size, shape, or crystalline structures of the MOF cores. Specifically, these branched multicompartment porous nanoparticles exhibit evasion behaviors in epithelial cells compared with macrophage cells, which may endow them great potential as a vehicle for immunotherapy.
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