Role of Diffusion Tensor Imaging Combined with Neuron-Specific Enolase and S100 calcium-binding protein B Detection in Predicting the Prognosis of Moderate and Severe Traumatic Brain Injury

烯醇化酶 创伤性脑损伤 部分各向异性 医学 格拉斯哥昏迷指数 磁共振弥散成像 内科学 格拉斯哥结局量表 胼胝体 胃肠病学 病理 磁共振成像 麻醉 免疫组织化学 放射科 精神科
作者
Peng Chen,Yu Xing,Tao Huang,Yongbing Deng,Jingrui Huang
出处
期刊:Iranian Red Crescent Medical Journal [DoNotEdit]
被引量:1
标识
DOI:10.32592/ircmj.2021.23.4.261
摘要

Background Traumatic brain injury (TBI) seriously affects the quality of life of patients. The present study evaluated the role of diffusion tensor imaging (DTI) combined with Neuron-Specific Enolase (NSE) and S100 calcium-binding protein B (S100B) protein in predicting the prognosis of moderate and severe TBI. Methods The TBI patients were divided into moderate TBI (TBIm) and severe TBI (TBIs) groups according to the Glasgow Coma Scale (GCS) after admission. The patients were then divided into good and poor prognosis groups according to the Glasgow Outcome Scale (GOS); moreover, their follow-ups were recorded at 3 and 6 months after injury. This study also included 65 healthy individuals with matched age and gender as the control group. The fractional anisotropy (FA) values of DTI, serum neuron-specific enolase (NSE), and S100B protein levels were detected in this study. The data were analyzed in SPSS software (version 22.0) to evaluate the role of DTI combined with NSE and S100B protein in predicting the prognosis in TBIm and TBIs. Results: After TBI, the FA values of DTI in the TBI group were lower than those in the control group (P<0.05); moreover, the serum NSE and S100B values in the TBI group were higher than those in the control group (P<0.05). In the TBIm patients, the FA values of the corpus callosum in the good prognosis group were higher than that in the poor prognosis group (P<0.05); however, there was no significant difference between the two groups regarding the FA values of the internal capsule and the cerebral peduncle (P>0.05). The serum levels of NSE and S100B in the good prognosis group were significantly lower than those in the poor prognosis group (P<0.05). In the TBIs patients, the FA value of all areas in the good prognosis group was significantly higher than that in the poor prognosis group (P<0.05). However, there was no significant difference between the two prognosis groups regarding the serum levels of NSE and S100B (P>0.05). Conclusion Although DTI combined with NSE and S100B protein can effectively predict the prognosis of patients with moderate and severe TBI in the early stages, various other measures have been used in the studies to predict the prognosis of TBI patients. Accordingly, comparison with other measures is essential in further studies.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
半颗橙子发布了新的文献求助10
刚刚
拓跋寡妇完成签到,获得积分10
刚刚
Jia发布了新的文献求助10
1秒前
Orange应助蓝醉澹翠妖娆采纳,获得10
2秒前
斯文谷秋发布了新的文献求助30
2秒前
长尾巴的人类完成签到,获得积分10
3秒前
LKSkywalker完成签到,获得积分10
4秒前
4秒前
研友_VZG7GZ应助机灵的南蕾采纳,获得10
4秒前
绿色的大嘴鸟完成签到 ,获得积分10
6秒前
6秒前
6秒前
哈哈和发布了新的文献求助10
8秒前
8秒前
8秒前
无花果应助Jia采纳,获得10
9秒前
赘婿应助乐乐采纳,获得10
10秒前
yyy完成签到,获得积分10
10秒前
134发布了新的文献求助10
11秒前
HF发布了新的文献求助10
11秒前
Owen应助机灵的千琴采纳,获得10
12秒前
maoyu发布了新的文献求助10
13秒前
zhou269完成签到,获得积分10
13秒前
顾矜应助GgvnMuu采纳,获得10
13秒前
14秒前
15秒前
搜集达人应助宋小姐冲鸭采纳,获得10
15秒前
Rosin发布了新的文献求助10
15秒前
17秒前
斯文谷秋发布了新的文献求助30
17秒前
su完成签到,获得积分10
18秒前
老王完成签到,获得积分10
20秒前
21秒前
21秒前
21秒前
21秒前
烟花应助自信白梦采纳,获得30
22秒前
22秒前
22秒前
Lucas应助王水水α采纳,获得10
22秒前
高分求助中
歯科矯正学 第7版(或第5版) 1004
The late Devonian Standard Conodont Zonation 1000
Semiconductor Process Reliability in Practice 1000
Smart but Scattered: The Revolutionary Executive Skills Approach to Helping Kids Reach Their Potential (第二版) 1000
PraxisRatgeber: Mantiden: Faszinierende Lauerjäger 700
Nickel superalloy market size, share, growth, trends, and forecast 2023-2030 600
Zeitschrift für Orient-Archäologie 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3236365
求助须知:如何正确求助?哪些是违规求助? 2882129
关于积分的说明 8225056
捐赠科研通 2550044
什么是DOI,文献DOI怎么找? 1379011
科研通“疑难数据库(出版商)”最低求助积分说明 648510
邀请新用户注册赠送积分活动 624047